Non‐surgical therapy for recurrent or persistent diseaseRadiation therapy and/or pharmacologic therapy for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas
It is very uncertain whether surgery alone changes non‐surgical therapy for recurrent or persistent diseaseRadiation… compared with preoperative pharmacological therapy and surgery (very low certainty).
1 finding from 1 review
Non‐surgical therapy for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical improvement ‐ Long‐term improvement: > 3 months · carpal tunnel syndrome
Surgery probably leads to higher clinical improvement ‐ Long‐term improvement: > 3 months compared with splint (moderate certainty).
1 finding from 1 review
Function ‐ Long‐term improvement: > 3 months · carpal tunnel syndrome
1 finding from 1 review
Pain VAS 0‐100 (higher means worse) · carpal tunnel syndrome
1 finding from 1 review
Health‐related quality of life ‐ Long‐term improvement: > 3 months · carpal tunnel syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · carpal tunnel syndrome
It is very uncertain whether surgery changes adverse effects compared with corticosteroid injection (very low certainty).
1 finding from 1 review
Need for surgery or secondary surgery during · carpal tunnel syndrome
It is very uncertain whether surgery changes need for surgery or secondary surgery during compared with corticosteroid injection (very low certainty).
1 finding from 1 review
CTS symptoms (Boston CTS questionnaire) ‐ long‐term improvement: > 3 monthsScale: 1 to 5, higher is worse · carpal tunnel syndrome
1 finding from 1 review
Function (Boston CTS questionnaire) ‐ Long‐term improvement: > 3 monthsScale: 1 to 5, higher is worse · carpal tunnel syndrome
1 finding from 1 review
Pain ‐ Long‐term improvement: > 3 months · carpal tunnel syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life (EQ‐5D) ‐ Long‐term improvement: > 3 months Scale: 0 to 1, higher is better · carpal tunnel syndrome
1 finding from 1 review
Adverse effects · carpal tunnel syndrome
It is very uncertain whether surgery changes adverse effects compared with splint (very low certainty).
1 finding from 1 review
Need for surgery or secondary surgery during · carpal tunnel syndrome
Surgery probably leads to lower need for surgery or secondary surgery during compared with splint (moderate certainty).
1 finding from 1 review
Clinical improvement ‐ Long‐term improvement: > 3 months · carpal tunnel syndrome
It is very uncertain whether surgery changes clinical improvement ‐ Long‐term improvement: > 3 months compared with corticosteroid injection (very low certainty).
1 finding from 1 review
Symptoms ‐ Long‐term improvement: > 3 months · carpal tunnel syndrome
1 finding from 1 review
Disease‐related complications · adults with growth‐hormone secreting pituitary adenomas
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · adults with growth‐hormone secreting pituitary adenomas
It is very uncertain whether surgery alone changes adverse events compared with preoperative pharmacological therapy and surgery (very low certainty).
1 finding from 1 review
All‐cause mortality · adults with growth‐hormone secreting pituitary adenomas
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Surgery for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas
It is very uncertain whether surgery alone changes surgery for recurrent or persistent disease compared with preoperative pharmacological therapy and surgery (very low certainty).
1 finding from 1 review