Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

557 questions · 600 findings · 75 reviews

No studies found 188 · 31.3%GRADE not reported 62 · 10.3%Very low 154 · 25.7%Low 122 · 20.3%Moderate 62 · 10.3%High 12 · 2%

Induction chemotherapy plus locoregional treatment (radiotherapy and/or surgery) vs Locoregional treatment (radiotherapy and/or surgery) alone

Overall survival, induction platinum + 5-fluorouracil prior to surgery vs surgery alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction platinum + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone (low certainty).

1 finding from 1 review

POP surgery with concomitant continence procedure vs no concomitant continence procedure

Vaginal POP surgery with vs without MUS · women with POP and SUI

POP surgery with concomitant continence procedure probably leads to lower vaginal POP surgery with vs without MUS compared with no concomitant continence procedure (moderate certainty).

2 findings from 1 review

POP surgery with concomitant continence procedure vs no concomitant continence procedure

Vaginal POP surgery with concomitant vs delayed continence surgery: additional concomitant MUS vs delayed MUS · women with POP and SUI

POP surgery with concomitant continence procedure showed no clear difference in vaginal POP surgery with concomitant vs delayed continence surgery:… compared with no concomitant continence procedure (moderate certainty).

1 finding from 1 review

POP surgery with concomitant continence procedure vs no concomitant continence procedure

Abdominal POP surgery with or without concomitant continence surgery: additional Burch colposuspension vs sacrocolpopexy alone · women with POP and SUI

POP surgery with concomitant continence procedure showed no clear difference in abdominal POP surgery with vs without concomitant continence… compared with no concomitant continence procedure (moderate certainty).

1 finding from 1 review

Prophylactic platelet transfusion prior to surgery vs alternative treatment

Number of participants with minor procedure‐related bleeding within 7 days of surgery · people with a low platelet count

It is very uncertain whether prophylactic platelet transfusion prior to surgery changes number of participants with minor procedure‐related bleeding within… compared with alternative treatments (very low certainty).

1 finding from 1 review

Endoscopic surgery vs open surgery

Resolution of symptoms · patients with trigger finger

It is very uncertain whether endoscopic surgery changes resolution of symptoms compared with open surgery (very low certainty).

1 finding from 1 review

Endoscopic surgery vs open surgery

Participant global assessment of success Not measured · patients with trigger finger

The review found no eligible studies for this question.

1 finding from 1 review

Endoscopic surgery vs open surgery

Adverse events (infection, dysaesthesia) · patients with trigger finger

It is very uncertain whether endoscopic surgery changes adverse events (infection, dysaesthesia) compared with open surgery (very low certainty).

1 finding from 1 review

Endoscopic surgery vs open surgery

Neurovascular injury · patients with trigger finger

It is very uncertain whether endoscopic surgery changes neurovascular injury compared with open surgery (very low certainty).

1 finding from 1 review