Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

111 questions · 112 findings · 23 reviews

No studies found 38 · 33.9%GRADE not reported 6 · 5.4%Very low 35 · 31.3%Low 16 · 14.3%Moderate 15 · 13.4%High 2 · 1.8%

Surgery vs any Medical Therapy

NON ‐ Healing (persistence or recurrence) · people with anal fissures

Any Surgery leads to lower NON ‐ Healing (persistence or recurrence) compared with any Medical Therapy (high certainty).

1 finding from 1 review

Hydrosurgery vs conventional 'open' surgical debridement

Post-operative infection · acute partial‐thickness burns prior to skin grafting

It is very uncertain whether hydrosurgery changes postoperative infection (number of participants with post‐operative… compared with conventional debridement (very low certainty).

1 finding from 1 review

Open surgery vs ERCP

Retained stones after primary intervention · with common bile duct stones

Open surgery probably leads to lower retained stones after primary intervention compared with ERCP (moderate certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Adverse events · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes adverse events compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review