Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

557 questions · 600 findings · 75 reviews

No studies found 188 · 31.3%GRADE not reported 62 · 10.3%Very low 154 · 25.7%Low 122 · 20.3%Moderate 62 · 10.3%High 12 · 2%

Prophylactic platelet transfusion prior to surgery vs alternative treatment

Serious adverse events (transfusion‐related adverse effects within 24 hours of the transfusion) · people with a low platelet count

It is very uncertain whether prophylactic platelet transfusion prior to surgery changes serious adverse events (transfusion‐related adverse effects within… compared with alternative treatments (very low certainty).

1 finding from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure

The proportion of pressure ulcers healed · people with venous leg ulcers

It is very uncertain whether subfascial endoscopic perforator vein surgery (SEPS) changes proportion of ulcers healed at 24 months compared with the Linton procedure (very low certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery probably leads to higher proportion of participants who were medication‐free (not using… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Mean change in unmedicated IOP24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in mean change in unmedicated IOP24 months (medium‐term) compared with phacoemulsification alone (high certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Mean change in daily IOP‐lowering medicationsat 24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in mean change in daily IOP‐lowering medicationsat 24 months… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants experiencing postoperative complicationsover 24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in proportion of participants experiencing postoperative… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO)

Dissatisfied with eating with denture · Edentulous patients requiring improved denture retention

Preprosthetic surgery for a conventional denture (PPS) showed no clear difference in dissatisfied with eating with denture compared with implant retained overdenture (dental implants) (IRO); GRADE not reported.

1 finding from 1 review

Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO)

Dissatisfied with appearance of denture · Edentulous patients requiring improved denture retention

Preprosthetic surgery for a conventional denture (PPS) showed no clear difference in dissatisfied with appearance of denture compared with implant retained overdenture (dental implants) (IRO); GRADE not reported.

1 finding from 1 review

Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO)

Overall denture satisfaction (0-10 scale) · Edentulous patients requiring improved denture retention

Preprosthetic surgery for a conventional denture (PPS) led to lower overall denture satisfaction (0-10 scale) compared with implant retained overdenture (dental implants) (IRO); GRADE not reported.

3 findings from 1 review