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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews · Neonatal

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No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 3 · 42.9%High 0 · 0%

Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT)

Death or bronchopulmonary dysplasia at 36 weeks PMA · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via thin catheter (S‐TC) probably leads to lower death or bronchopulmonary dysplasia (BPD) at 36 weeks' postmenstrual… compared with surfactant administration through an endotracheal tube (S‐ETT) (moderate certainty).

1 finding from 1 review

Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT)

Need for intubation within the first 72 hours · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via thin catheter (S‐TC) probably leads to lower need for intubation within the first 72 hours compared with surfactant administration through an endotracheal tube (S‐ETT) (moderate certainty).

1 finding from 1 review

Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT)

Air leak requiring drainage · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via thin catheter (S‐TC) showed no clear difference in air leak requiring drainage compared with surfactant administration through an endotracheal tube (S‐ETT) (low certainty).

1 finding from 1 review

Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT)

Severe intraventricular haemorrhage · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via thin catheter (S‐TC) may leads to lower severe intraventricular haemorrhage (grade III or IV) compared with surfactant administration through an endotracheal tube (S‐ETT) (low certainty).

1 finding from 1 review

Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT)

Death during first hospitalisation (all causes) · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via thin catheter (S‐TC) may leads to lower death during first hospitalisation (all causes) compared with surfactant administration through an endotracheal tube (S‐ETT) (low certainty).

1 finding from 1 review

Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT)

Bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via thin catheter (S‐TC) probably leads to lower bronchopulmonary dysplasia (BPD) among survivors at 36 weeks'… compared with surfactant administration through an endotracheal tube (S‐ETT) (moderate certainty).

1 finding from 1 review

Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT)

Death or survival with neurosensory disability ‐ not reported · preterm infants with or at risk of respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review