Question · asked by 1 review

Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT): Severe intraventricular haemorrhage

Surfactant administration via thin catheter (S‐TC) may leads to lower severe intraventricular haemorrhage (grade III or IV) compared with surfactant administration through an endotracheal tube (S‐ETT) (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT)
Severe intraventricular haemorrhage (grade III or IV) · preterm infants with or at risk of respiratory distress syndrome
Surfactant administration via thin catheter (S‐TC) may leads to lower severe intraventricular haemorrhage (grade III or IV) compared with surfactant administration through an endotracheal tube (S‐ETT) (low certainty).
Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome (2021) · Cochrane Headline outcomes only
RR 0.63 [0.42, 0.96]5 studies · 857 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.