Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4 questions · 4 findings · 4 reviews

No studies found 1 · 25%GRADE not reported 1 · 25%Very low 1 · 25%Low 0 · 0%Moderate 0 · 0%High 1 · 25%

Statins vs placebo

Discontinuation of medication due to adverse events · older people with normal cognitiona

Statins showed no clear difference in adverse events leading to discontinuation of therapy compared with placebo (high certainty).

1 finding from 1 review

Statins with cholesterol supplementation vs cholesterol supplementation only

Statin‐related adverse events · children and adults with Smith‐Lemli‐Opitz syndrome

It is very uncertain whether statins with cholesterol supplementation changes statin‐related adverse events compared with cholesterol supplementation only (very low certainty).

1 finding from 1 review