Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

50 questions · 56 findings · 6 reviews

No studies found 11 · 19.6%GRADE not reported 4 · 7.1%Very low 22 · 39.3%Low 14 · 25%Moderate 2 · 3.6%High 3 · 5.4%

Pharmacological interventions vs placebo

Smoking cessation · young people

It is very uncertain whether pharmacological interventions changes bupropion vs placebo Smoking cessation compared with placebo (very low certainty).

3 findings from 1 review

Pharmacological interventions vs placebo

Adverse events (control ‐ placebo) · young people
3 findings from 1 review

Antidepressants vs placebo

Adverse events: death ‐ at end of treatment (Analysis 1.14) · people with stroke

It is very uncertain whether pharmacological interventions (antidepressants) changes adverse events: death ‐ at end of treatment Analysis 1.12 compared with placebo (very low certainty).

1 finding from 1 review