What do systematic reviews say?

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: baclofen versus clonidine compared with other pharmacological detoxification treatment (very low certainty).

• Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
  RR 1.06 [0.63, 1.8]
  66 participants
  Very low
• Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
  RR 2.01 [1.69, 2.38]
  361 participants
  Low

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus clonidine plus amantadine,… compared with other pharmacological detoxification treatment (very low certainty).

• Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
  RR 1.03 [0.86, 1.24]
  69 participants
  Very low

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus buprenorphine, inpatient… compared with other pharmacological detoxification treatment (very low certainty).

• Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
  RR 1.04 [0.9, 1.2]
  35 participants
  Very low

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

• Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
  no estimate extracted
  60 participants
  Very low
• Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
  no estimate extracted
  34 participants
  Very low