Participant‐reported pain relief of 50% or greater · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…
Paracetamol (single oral dose, any dose or formulation; subgroups up… led to higher achieving at least 50% pain relief at 6 hours (using pain relief… compared with placebo; GRADE not reported.
1 finding from 1 review
Postoperative pain (dichotomous measure: parent report of presence of pain-related behaviours) · Children and adolescents having dental treatment under local anaesthetic (restorative and extraction treatments)
Preoperative paracetamol (acetaminophen) showed no clear difference in postoperative pain (dichotomous measure: parent report of presence… compared with placebo (low certainty).
1 finding from 1 review
Adverse events · Children and adolescents having dental treatment under local anaesthetic (restorative and extraction treatments)
1 finding from 1 review
Pain with dilation ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain with aspiration ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain during procedurea,b · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
1 finding from 1 review
Pain with dilation ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain with aspiration ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain during procedurea,b · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) probably leads to lower pain intensity (VAS 0-100 mm) compared with control (placebo or no treatment) (moderate certainty).
3 findings from 1 review
MD -11.66 [-16.15, -7.17]
10 studies · 685 participants
Moderate
MD -21.19 [-28.31, -14.06]
12 studies · 1012 participants
Moderate
MD -24.27 [-31.44, -17.11]
9 studies · 535 participants
Moderate
Quality of life or participant satisfaction · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
1 finding from 1 review
Rescue analgesia · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
1 finding from 1 review
Time off school or work · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
Failure to complete orthodontic treatment due to pain · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review