Primary outcome: partial clinical response · patients with cutaneous disease in systemic lupus erythematosus
1 finding from 1 review
Secondary outcome: clinical flare · patients with cutaneous disease in systemic lupus erythematosus
1 finding from 1 review
Secondary outcome: CLASI · patients with cutaneous disease in systemic lupus erythematosus
1 finding from 1 review
Secondary outcome: Dermatology Quality of Life measure · patients with cutaneous disease in systemic lupus erythematosus
1 finding from 1 review
Adverse events: severe · patients with cutaneous disease in systemic lupus erythematosus
Oral chloroquine showed no clear difference in adverse events: severe compared with placebo (low certainty).
1 finding from 1 review
Minor adverse events · patients with cutaneous disease in systemic lupus erythematosus
1 finding from 1 review
Change in disability score · children and adults with SMA types II and III
2 findings from 1 review
Muscle strength · children and adults with SMA types II and III
1 finding from 1 review
Acquiring the ability to stand or walk · children and adults with SMA types II and III
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in quality of life · children and adults with SMA types II and III
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in pulmonary function · children and adults with SMA types II and III
1 finding from 1 review
Time from beginning of treatment until death or full‐time ventilation · children and adults with SMA types II and III
1 finding from 1 review
Adverse events related to treatment · children and adults with SMA types II and III
1 finding from 1 review
Probing pocket depth · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review
Dental caries · Children or adults (fit and healthy, or with a well-defined medical condition)
It is very uncertain whether any form of one-to-one oral hygiene advice (OHA) changes dental caries compared with no OHA (very low certainty).
1 finding from 1 review
SoF: 1 study in adults reported only 'small and statistically insignificant changes' but no usable data; the other study on infants provided evidence of a benefit for OHA at 8 and 12 months but not at 4 months.…
2 studies · 244 participants
Very low
Gingivitis · Children or adults (fit and healthy, or with a well-defined medical condition)
It is very uncertain whether any form of one-to-one oral hygiene advice (OHA) changes periodontal health: gingivitis compared with no OHA (very low certainty).
1 finding from 1 review
SoF: 1 small study in adults had contradictory results at 3 and 6 months; the other study in adults showed evidence of a benefit for OHA at all time points (12, 24, 36 months). Results: Hetland 1982 MD 0.25 (0.05 to…
2 studies · 235 participants
Very low
Patient-reported changes in knowledge, attitudes and quality of life · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review
Hoogstraten 1983 (dental knowledge, attitude, behaviour, fear of dental treatment) and Memarpour 2016 (parents' knowledge and performance regarding oral health); measured, not synthesised or GRADE-rated.
2 studies
GRADE not reported
Clearance, as assessed by a clinician at any · infantile haemangiomas (strawberry birthmarks) of the skin
Oral propranolol probably leads to higher clearance, as assessed by a clinician at any compared with placebo (moderate certainty).
1 finding from 1 review
Clearance, as assessed by a clinician at any · infantile haemangiomas (strawberry birthmarks) of the skin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
A subjective measure of improvement, as assessed by the parent or child, at any · infantile haemangiomas (strawberry birthmarks) of the skin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found