Breastfeeding · increasing breast milk production in mothers of non‐hospitalised term infants
1 finding from 1 review
Infant weight (where they were only receiving own mother's milk) at the end of the study (grams) ( · increasing breast milk production in mothers of non‐hospitalised term infants
1 finding from 1 review
Volume of breast milk at the latest time measured (mL) ( · increasing breast milk production in mothers of non‐hospitalised term infants
1 finding from 1 review
Adverse effects for the infant or mother · increasing breast milk production in mothers of non‐hospitalised term infants
1 finding from 1 review
new root-surface carious lesions or restorations · community-dwelling older adults with root caries
SDF plus potassium iodide had a 52% preventative fraction; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months) · benzydamine hydrochloride
SoF9 Topical treatments vs placebo. Symptom relief short-term: insufficient or contradictory evidence regarding benefit of any evaluated topical treatment; 150 participants (4 RCTs); very low. Subgroups: benzydamine (1…
4 studies · 150 participants
Very low
Adverse effects · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether topical treatments (lactoperoxidase oral rinse / Biotene) changes relief of burning/discomfort (symptom relief; pain intensity) compared with placebo (very low certainty).
1 finding from 1 review
Participant‐reported pain relief of 50% or greater · Patients with pain after surgical removal of lower wisdom teeth (third molars) requiring bone removal or with baseline moderate to severe…
Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) leads to higher proportion of patients with >50% maximum pain relief (TOTPAR) over 6… compared with paracetamol (acetaminophen) (single postoperative oral dose; 600 mg… (high certainty).
1 finding from 1 review
Proportion of patients with >50% maximum pain relief (TOTPAR) over 2 hours · Patients with pain after surgical removal of lower wisdom teeth (third molars) requiring bone removal or with baseline moderate to severe…
Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) leads to higher proportion of patients with >50% maximum pain relief (TOTPAR) over 2… compared with paracetamol (acetaminophen) (single postoperative oral dose; 600 mg… (high certainty).
1 finding from 1 review
Patients not using rescue medication at 6 hours · Patients with pain after surgical removal of lower wisdom teeth (third molars) requiring bone removal or with baseline moderate to severe…
Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) leads to higher patients not using rescue medication at 6 hours compared with paracetamol (acetaminophen) (single postoperative oral dose; 600 mg… (high certainty).
1 finding from 1 review
Use of rescue medication · Patients with pain after surgical removal of lower wisdom teeth (third molars) requiring bone removal or with baseline moderate to severe…
Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) led to higher patients using rescue medication at 8 hours compared with paracetamol (acetaminophen) (single postoperative oral dose; 600 mg…; GRADE not reported.
1 finding from 1 review
RR 2.02 [1.57, 2.60]
2 studies
GRADE not reported
Adverse events · Patients with pain after surgical removal of lower wisdom teeth (third molars) requiring bone removal or with baseline moderate to severe…
1 finding from 1 review
The majority of adverse events were minor in nature and usually included nausea, vomiting, headaches and dizziness. Side effect profiles have not been included in a meta-analysis as multiple adverse events were…
7 studies
GRADE not reported
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Patients with osteoarthritis of the knee or hip
Oral or transdermal opioids showed no clear difference in pain intensity Various pain scales. (median compared with placebo (high certainty).
1 finding from 1 review
Function Various validated function scales. · Patients with osteoarthritis of the knee or hip
Oral or transdermal opioids showed no clear difference in function Various validated function scales. (median compared with placebo (high certainty).
1 finding from 1 review
Adverse events as N of participants with at least one adverse event objective · Patients with osteoarthritis of the knee or hip
Oral or transdermal opioids probably leads to higher number of participants experiencing any adverse event (median compared with placebo (moderate certainty).
1 finding from 1 review
Number of patients who withdrew because of adverse events · Patients with osteoarthritis of the knee or hip
Oral or transdermal opioids leads to higher number of participants who withdrew because of adverse events (median compared with placebo (high certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · Patients with osteoarthritis of the knee or hip
Oral or transdermal opioids showed no clear difference in number of participants experiencing any serious adverse event (median compared with placebo (low certainty).
1 finding from 1 review
Withdrawal symptoms · Patients with osteoarthritis of the knee or hip
Oral or transdermal opioids probably leads to higher withdrawal symptoms (median compared with placebo (moderate certainty).
1 finding from 1 review
Diabetes complications
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found