Adverse events: severe · patients with cutaneous disease in systemic lupus erythematosus
Oral ciclosporin showed no clear difference in adverse events: severe compared with oral azathioprine (low certainty).
1 finding from 1 review
Adverse events: minor (hirsutism) · patients with cutaneous disease in systemic lupus erythematosus
Oral ciclosporin may leads to higher adverse events: minor (hirsutism) compared with oral azathioprine (low certainty).
1 finding from 1 review
Safety of the intervention (adverse effects) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
SoF 3, Safety of the intervention over 3 months: systemic celecoxib (1 study) - 32 intervention participants reported 56 adverse effects, 20 placebo participants reported 20; 4 grade 3 events; 2 discontinued. Ketorolac…
2 studies
GRADE not reported
Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia
The review found no eligible studies for this question.
1 finding from 1 review
Quality of life: Chronic pain · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
The review found no eligible studies for this question.
1 finding from 1 review
Dental state: No clinically important change in plaque index · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
It is very uncertain whether motivational interview plus oral health education changes dental state: No clinically important change in plaque index compared with oral health education (very low certainty).
1 finding from 1 review
Self regulation: Average score (Treatment Self Regulation Questionnaire, high score = good) · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
Motivational interview plus oral health education showed no clear difference in self regulation: Average score (Treatment Self Regulation… compared with oral health education; GRADE not reported.
3 findings from 1 review
MD 0.2 [-0.93, 1.33]
1 study · 56 participants
GRADE not reported
MD 0.7 [-0.43, 1.83]
1 study · 56 participants
GRADE not reported
MD 1.1 [0.22, 1.98]
1 study · 56 participants
GRADE not reported
Leaving the study early · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
Motivational interview plus oral health education showed no clear difference in leaving the study early compared with oral health education (moderate certainty).
1 finding from 1 review
Adverse events: Clinically important specific adverse events · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
The review found no eligible studies for this question.
1 finding from 1 review
Service use: Emergency medical/dental treatment · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
The review found no eligible studies for this question.
1 finding from 1 review
Sensitivity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions
1 finding from 1 review
Specificity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in incidence of VAP compared with manual toothbrushing (standard oral care); GRADE not reported.
1 finding from 1 review
Duration of ICU stay · Critically ill patients receiving mechanical ventilation in ICU
Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in duration of ICU stay compared with manual toothbrushing (standard oral care); GRADE not reported.
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in mortality compared with manual toothbrushing (standard oral care); GRADE not reported.
1 finding from 1 review
Duration of mechanical ventilation · Critically ill patients receiving mechanical ventilation in ICU
Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in duration of mechanical ventilation compared with manual toothbrushing (standard oral care); GRADE not reported.
1 finding from 1 review
Complete response · patients with cutaneous disease in systemic lupus erythematosus
Oral methotrexate showed no clear difference in primary outcome: complete clinical response compared with oral chloroquine (low certainty).
1 finding from 1 review
Primary outcome: partial clinical response · patients with cutaneous disease in systemic lupus erythematosus
1 finding from 1 review
Secondary outcome: clinical flare · patients with cutaneous disease in systemic lupus erythematosus
1 finding from 1 review
Secondary outcome: Dermatology Quality of Life measure · patients with cutaneous disease in systemic lupus erythematosus
1 finding from 1 review