Drug responders · RLS
Opioids may leads to higher drug responders compared with placebo (low certainty).
2 findings from 1 review
Remitters · RLS
Opioids may leads to higher remitters compared with placebo (low certainty).
1 finding from 1 review
Adverse events · RLS
Opioids may leads to higher adverse Events compared with placebo (low certainty).
1 finding from 1 review
Quality of life · RLS
1 finding from 1 review
PGIC very much improved · adults with sickle cell disease in a vaso‐occlusive crisis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient Global Impression of Change much or very much improved · adults with sickle cell disease in a vaso‐occlusive crisis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Any adverse event · adults with sickle cell disease in a vaso‐occlusive crisis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse event · adults with sickle cell disease in a vaso‐occlusive crisis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Withdrawals due to adverse events · adults with sickle cell disease in a vaso‐occlusive crisis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participant‐reported pain relief of 50% or greater · adults with sickle cell disease in a vaso‐occlusive crisis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participant‐reported pain relief of 30% or greater · adults with sickle cell disease in a vaso‐occlusive crisis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
PGIC very much improved · adults with sickle cell disease in a vaso‐occlusive crisis
1 finding from 1 review
Patient Global Impression of Change much or very much improved · adults with sickle cell disease in a vaso‐occlusive crisis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Any adverse event ( · adults with sickle cell disease in a vaso‐occlusive crisis
1 finding from 1 review
Serious adverse event ( · adults with sickle cell disease in a vaso‐occlusive crisis
1 finding from 1 review
Withdrawals due to adverse events · adults with sickle cell disease in a vaso‐occlusive crisis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participant‐reported pain relief of 50% or greater · adults with sickle cell disease in a vaso‐occlusive crisis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participant‐reported pain relief of 30% or greater · adults with sickle cell disease in a vaso‐occlusive crisis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intraoperative bradycardia (yes/no) · adults undergoing surgery
Preventive opioids showed no clear difference in intraoperative bradycardia (yes/no) compared with postincision opioids (low certainty).
1 finding from 1 review
Intraoperative hypotension (yes/no) · adults undergoing surgery
Preventive opioids showed no clear difference in intraoperative hypotension (yes/no) compared with postincision opioids (low certainty).
1 finding from 1 review