Adverse events
It is very uncertain whether NSAIDs changes adverse events compared with placebo (very low certainty).
1 finding from 1 review
Adverse events
It is very uncertain whether NSAIDs changes adverse events compared with paracetamol (very low certainty).
1 finding from 1 review
All topical NSAIDs Local adverse events · adults with strains, sprains, or muscle pull
1 finding from 1 review
All topical NSAIDs Systemic adverse events · adults with strains, sprains, or muscle pull
1 finding from 1 review
Total adverse events · acute gout
NSAIDs probably leads to higher total adverse events compared with glucocorticoids (moderate certainty).
1 finding from 1 review
RR 1.62 [1.03, 2.55]
Studies not reported
Moderate
Total adverse events · acute gout
NSAIDs showed no clear difference in total adverse events compared with placebo (low certainty).
1 finding from 1 review
RR 0.2 [0.01, 3.85]
Studies not reported
Low
All topical NSAIDs Withdrawals ‐ adverse events · adults with strains, sprains, or muscle pull
1 finding from 1 review
Withdrawals due to adverse events · acute gout
NSAIDs showed no clear difference in withdrawals due to adverse events compared with glucocorticoids (moderate certainty).
1 finding from 1 review
RR 2.8 [0.55, 14.22]
Studies not reported
Moderate
Withdrawals due to adverse events · acute gout
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Proportion of participants experiencing adverse events · Patients with acute low‐back pain
It is very uncertain whether NSAIDs changes proportion of participants experiencing adverse events compared with placebo (very low certainty).
1 finding from 1 review
Adverse events · Adults with lateral elbow pain
1 finding from 1 review
Adverse events · Adults with lateral elbow pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · Adults with lateral elbow pain
Topical NSAIDs showed no clear difference in adverse events compared with placebo (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · Adults with lateral elbow pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Withdrawals due to adverse events · Adults with lateral elbow pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of serious adverse events · patients with axSpA (AS and nr‐axSpA)
COX‐2 NSAIDs showed no clear difference in number of serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review
RR 0.92 [0.14, 6.21]
669 participants
Moderate
Serious adverse events · adults with strains, sprains, or muscle pull
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Withdrawals due to adverse events · patients with axSpA (AS and nr‐axSpA)
COX‐2 NSAIDs showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).
1 finding from 1 review
RR 2.14 [0.36, 12.56]
669 participants
Low
Withdrawals due to adverse events · Adults with lateral elbow pain
1 finding from 1 review
Adverse effects ‐ Stroke · cognitively healthy people in late life
Other NSAIDs showed no clear difference in adverse events – stroke compared with placebo (moderate certainty).
1 finding from 1 review