What do systematic reviews say?

NPWT vs standard dressing

The review found no eligible studies for this question.

• Negative pressure wound therapy for treating pressure ulcers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT vs standard dressing

The review found no eligible studies for this question.

• Negative pressure wound therapy for treating pressure ulcers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT vs moist wound healing

The review found no eligible studies for this question.

• Negative pressure wound therapy for treating pressure ulcers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT vs moist wound healing

The review found no eligible studies for this question.

• Negative pressure wound therapy for treating pressure ulcers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT vs the Healthpoint system

• Negative pressure wound therapy for treating pressure ulcers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 28 participants
  GRADE not reported

NPWT vs the Healthpoint system

The review found no eligible studies for this question.

• Negative pressure wound therapy for treating pressure ulcers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT vs dressings

NPWT may leads to higher proportion of wounds healed compared with dressings (low certainty).

• Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus 2018 · Cochrane Headline outcomes only
  RR 1.44 [1.03, 2.01]
  1 study · 162 participants
  Low
• Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus 2018 · Cochrane Headline outcomes only
  RR 1.4 [1.14, 1.72]
  5 studies · 486 participants
  Low

NPWT vs dressings

NPWT showed no clear difference in number of wounds closed or covered with surgery compared with dressings (low certainty).

• Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus 2018 · Cochrane Headline outcomes only
  RR 1.02 [0.85, 1.24]
  3 studies · 129 participants
  Low
• Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus 2018 · Cochrane Headline outcomes only
  RR 1.02 [0.95, 1.09]
  1 study · 130 participants
  Very low

NPWT vs dressings

It is very uncertain whether NPWT changes wound recurrence compared with dressings (very low certainty).

• Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus 2018 · Cochrane Headline outcomes only
  RR 0.5 [0.1, 2.53]
  1 study · 60 participants
  Very low
• Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 75 mmHg vs usual care

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 75 mmHg vs usual care

It is very uncertain whether NPWT 75 mmHg changes wound infection compared with standard care (very low certainty).

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  RR 0.44 [0.17, 1.1]
  1 study · 463 participants
  Very low

NPWT 125 mmHg vs usual care

NPWT 125 mmHg showed no clear difference in complete wound healing compared with standard care (moderate certainty).

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  RR 1.01 [0.81, 1.27]
  1 study · 460 participants
  Moderate

NPWT 125 mmHg vs NPWT 75 mmHg

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 125 mmHg vs NPWT 75 mmHg

It is very uncertain whether NPWT 125 mmHg changes wound infection compared with NPWT 75 mmHg (very low certainty).

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  RR 1.04 [0.31, 3.51]
  1 study · 251 participants
  Very low

NPWT 125 mmHg vs usual care

It is very uncertain whether NPWT 125 mmHg changes wound infection compared with standard care (very low certainty).

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  RR 0.48 [0.2, 1.13]
  4 studies · 596 participants
  Very low

NPWT 125 mmHg vs usual care

The review found no eligible studies for this question.

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT 125 mmHg vs usual care

NPWT 125 mmHg showed no clear difference in wound infection compared with standard care (low certainty).

• Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
  RR 0.61 [0.31, 1.18]
  2 studies · 509 participants
  Low

NPWT vs standard dressing

It is very uncertain whether NPWT changes adverse events compared with standard dressings therapy (very low certainty).

• Negative pressure wound therapy for treating pressure ulcers 2023 · Cochrane Headline outcomes only
  RR 1.25 [0.64, 2.44]
  1 study · 12 participants
  Very low

NPWT vs moist wound healing

The review found no eligible studies for this question.

• Negative pressure wound therapy for treating pressure ulcers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT combined with internet‐plus home care vs usual care

• Negative pressure wound therapy for treating pressure ulcers 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  GRADE not reported