Diarrhoea · early fetal death (less than 24 weeks)
Vaginal misoprostol showed no clear difference in diarrhoea compared with placebo (low certainty).
1 finding from 1 review
Blood loss: haemoglobin difference > 10 g/L · early fetal death (less than 24 weeks)
It is very uncertain whether vaginal misoprostol changes blood loss: haemoglobin difference > 10 g/L compared with placebo (very low certainty).
1 finding from 1 review
Opiate use (as a proxy measure for pain) for all participants on ITT (including those without confirmed AMI) · early fetal death (less than 24 weeks)
It is very uncertain whether vaginal misoprostol changes pain (opiate use) compared with placebo (very low certainty).
1 finding from 1 review
Woman’s satisfaction/acceptability of method · early fetal death (less than 24 weeks)
Vaginal misoprostol showed no clear difference in woman’s satisfaction/acceptability of method compared with placebo (low certainty).
1 finding from 1 review
Complete miscarriage · early fetal death (less than 24 weeks)
Vaginal misoprostol may leads to lower complete miscarriage compared with surgical evacuation of uterus (low certainty).
1 finding from 1 review
Pelvic infection · early fetal death (less than 24 weeks)
Vaginal misoprostol showed no clear difference in pelvic infection compared with surgical evacuation of uterus (low certainty).
1 finding from 1 review
Vaginal delivery not achieved within 24 hours · women requiring induction of labour
1 finding from 1 review
Vaginal birth not achieved in 48 to 72 h · women requiring induction of labour
1 finding from 1 review
Uterine hyperstimulation with fetal heart rate changes · women requiring induction of labour
Vaginal misoprostol showed no clear difference in uterine hyperstimulation (with fetal heart rate changes) compared with placebo (low certainty).
1 finding from 1 review
Caesarean section · women requiring induction of labour
Vaginal misoprostol showed no clear difference in caesarean section compared with placebo (low certainty).
1 finding from 1 review
Neonatal death or serious neonatal perinatal morbidity · women requiring induction of labour
Vaginal misoprostol showed no clear difference in serious neonatal morbidity or death compared with placebo (low certainty).
1 finding from 1 review
Serious maternal morbidity or death · women requiring induction of labour
1 finding from 1 review
Admission to neonatal intensive care unit · women requiring induction of labour
Vaginal misoprostol showed no clear difference in neonatal intensive care unit admission compared with placebo (low certainty).
1 finding from 1 review
Serious maternal morbidity or death · women with a previous caesarean section
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Vaginal delivery not achieved within 24 hours · women with a previous caesarean section
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Uterine hyperstimulation with fetal heart rate changes · women with a previous caesarean section
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Caesarean section · women with a previous caesarean section
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious neonatal morbidity or perinatal death · women with a previous caesarean section
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Failure to achieve complete abortion · women undergoing first trimester abortion
Misoprostol 800 µg plus mifepristone 200 mg probably leads to lower failure to achieve complete abortion compared with misoprostol 400 µg plus mifepristone 200 mg (moderate certainty).
1 finding from 1 review
Nausea · women undergoing first trimester abortion
Misoprostol 800 µg plus mifepristone 200 mg showed no clear difference in nausea compared with misoprostol 400 µg plus mifepristone 200 mg (moderate certainty).
1 finding from 1 review