Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

234 questions · 264 findings · 18 reviews

No studies found 72 · 27.3%GRADE not reported 15 · 5.7%Very low 84 · 31.8%Low 64 · 24.2%Moderate 24 · 9.1%High 5 · 1.9%

Metformin vs megestrol

Hysterectomy rate · endometrial hyperplasia

It is very uncertain whether summary of findings table ‐ Metformin changes hysterectomy rate compared with megestrol (very low certainty).

1 finding from 1 review

Metformin vs megestrol

Abnormal uterine bleeding · endometrial hyperplasia

It is very uncertain whether summary of findings table ‐ Metformin changes abnormal uterine bleeding compared with megestrol (very low certainty).

1 finding from 1 review

Metformin vs megestrol

Adverse effects during treatment ‐ not reported · endometrial hyperplasia

The review found no eligible studies for this question.

1 finding from 1 review