Hospitalisation (any cause) · adults with bronchiectasis
Macrolides showed no clear difference in hospitalisation: all cause compared with placebo (low certainty).
1 finding from 1 review
Serious adverse events ‐ not reported · children with bronchiectasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · children with bronchiectasis
1 finding from 1 review
Quality of life ‐ not reported · children with bronchiectasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events · adults with bronchiectasis
Macrolides showed no clear difference in serious adverse events compared with placebo (low certainty).
1 finding from 1 review
All‐cause mortality · adults with bronchiectasis
1 finding from 1 review
Quality of life: 1a. Average endpoint scores on various scales (MSQoL‐54, high = good) ‐ short term · adults with bronchiectasis
1 finding from 1 review
Quality of life: change · adults with bronchiectasis
1 finding from 1 review
Exacerbations (number of people experiencing ≥ 1 exacerbations) · adults with bronchiectasis
Macrolides showed no clear difference in ≥ 1 exacerbation compared with no intervention (moderate certainty).
1 finding from 1 review
Hospitalisation ‐ not reported · adults with bronchiectasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events ‐ not reported · adults with bronchiectasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical cure: syndromic approach · sexually active adults
Macrolides showed no clear difference in clinical cure: syndromic approach compared with any other antibiotic (low certainty).
1 finding from 1 review
Clinical cure: aetiological approach · sexually active adults
Macrolides showed no clear difference in clinical cure: aetiological approach compared with any other antibiotic (low certainty).
1 finding from 1 review
Clinical improvement: syndromic approach · sexually active adults
It is very uncertain whether macrolides changes clinical improvement: syndromic approach compared with any other antibiotic (very low certainty).
1 finding from 1 review
Clinical improvement: aetiological approach · sexually active adults
Macrolides showed no clear difference in clinical improvement: aetiological approach compared with any other antibiotic (low certainty).
1 finding from 1 review
Microbiological cure · sexually active adults
Macrolides showed no clear difference in microbiological cure compared with any other antibiotic (low certainty).
1 finding from 1 review
Minor adverse events · sexually active adults
It is very uncertain whether macrolides changes minor adverse events compared with any other antibiotic (very low certainty).
1 finding from 1 review
Resolution of symptoms post‐treatment (ITT analysis) · group A streptococcal pharyngitis
Macrolides showed no clear difference in resolution of symptoms post‐treatment (ITT analysis) compared with penicillin (low certainty).
1 finding from 1 review
Resolution of symptoms post‐treatment (evaluable participants) · group A streptococcal pharyngitis
Macrolides showed no clear difference in resolution of symptoms post‐treatment (evaluable participants) compared with penicillin (low certainty).
1 finding from 1 review
Relapse · group A streptococcal pharyngitis
Macrolides showed no clear difference in incidence of relapse (evaluable participants) compared with penicillin (low certainty).
1 finding from 1 review