Findings

What do systematic reviews say?

8 questions · 8 findings · 5 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 2 · 25%GRADE not reported 0 · 0%Very low 2 · 25%Low 4 · 50%Moderate 0 · 0%High 0 · 0%

Macrolides vs other antibiotics

Minor adverse events · sexually active adults

It is very uncertain whether macrolides changes minor adverse events compared with any other antibiotic (very low certainty).

1 finding from 1 review

Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults 2017 · Cochrane Headline outcomes only
RR 1.34 [0.24, 7.51]
3 studies · 412 participants
Very low

Regimens containing macrolides (azithromycin) vs regimens containing tetracycline (doxycycline)

Adverse events: any antibiotic‐related adverse event leading to discontinuation of therapy · women with PID

Regimens containing macrolides (azithromycin) showed no clear difference in adverse events: any antibiotic‐related adverse event leading to… compared with regimens containing tetracycline (doxycycline) (low certainty).

1 finding from 1 review

Antibiotic therapy for pelvic inflammatory disease 2020 · Cochrane Headline outcomes only
RR 0.71 [0.38, 1.34]
Studies not reported
Low

Macrolides vs doxycycline

Serious adverse events · adults and adolescents with scrub typhus

1 finding from 1 review

Antibiotics for treating scrub typhus 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 242 participants
Very low

Macrolides vs placebo

Serious adverse events · children with bronchiectasis

Macrolides showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Macrolide antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
OR 0.43 [0.17, 1.05]
1 study · 89 participants
Low

Macrolides vs placebo

Serious adverse events · adults with bronchiectasis

Macrolides showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Macrolide antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
OR 0.49 [0.2, 1.23]
3 studies · 326 participants
Low

Macrolides vs penicillin

Adverse events (ITT analysis) · group A streptococcal pharyngitis

Macrolides showed no clear difference in adverse events (ITT analysis) compared with penicillin (low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 1.19 [0.82, 1.73]
6 studies · 1727 participants
Low

Macrolides vs no intervention

Serious adverse events ‐ not reported · children with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

Macrolide antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Macrolides vs no intervention

Serious adverse events ‐ not reported · adults with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

Macrolide antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found