Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

450 questions · 474 findings · 58 reviews

No studies found 96 · 20.3%GRADE not reported 49 · 10.3%Very low 102 · 21.5%Low 110 · 23.2%Moderate 77 · 16.2%High 40 · 8.4%

IVIg vs placebo or no treatment

Event‐free survival (no death, transplant, or left ventricular assist device) ‐ adults with myocarditis · adults with acute myocarditis

It is very uncertain whether intravenous immunoglobulin changes event‐free survival (risk of death, cardiac transplant, or left… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

IVIg vs placebo or no treatment

Overall survival (risk of death) ‐ adults with myocarditis, median · adults with acute myocarditis

It is very uncertain whether intravenous immunoglobulin changes overall survival (risk of death) ‐ adults with myocarditis, median compared with placebo or no treatment (very low certainty).

1 finding from 1 review

IVIg vs placebo or no treatment

Overall survival (risk of death) ‐ children with myocarditis, 6‐month · children with acute myocarditis

It is very uncertain whether intravenous immunoglobulin changes overall survival (risk of death) ‐ children with myocarditis, 6‐month compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Lidocaine IV vs placebo or no treatment

Nausea · adults undergoing surgery with general anaesthesia

It is very uncertain whether intravenous (IV) lidocaine changes postoperative nausea, 'overall' (0 to 24 h, to 48 h, to 72 h) compared with placebo or no treatment (very low certainty).

1 finding from 1 review