IVIg vs placebo or no treatment: Event‐free survival (no death, transplant, or left ventricular assist device) ‐ adults with myocarditis
It is very uncertain whether intravenous immunoglobulin changes event‐free survival (risk of death, cardiac transplant, or left… compared with placebo or no treatment (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Intravenous immunoglobulin vs placebo or no treatment Event‐free survival (risk of death, cardiac transplant, or left ventricular assist device) ‐ adults with myocarditis, median · adults with acute myocarditis It is very uncertain whether intravenous immunoglobulin changes event‐free survival (risk of death, cardiac transplant, or left… compared with placebo or no treatment (very low certainty). Intravenous immunoglobulin for presumed viral myocarditis in children and adults (2020) · Cochrane Headline outcomes only | RR 1.76 [0.48, 6.4] | 1 study · 62 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Intravenous immunoglobulin for presumed viral myocarditis in children and adults 2020 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.