Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

83 questions · 89 findings · 10 reviews

No studies found 31 · 34.8%GRADE not reported 3 · 3.4%Very low 12 · 13.5%Low 19 · 21.3%Moderate 19 · 21.3%High 5 · 5.6%

IVIg vs SCIg

Proportion of IVIg‐treated participants with an increase in disability during controlled IVIg withdrawal · people with multifocal motor neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

IVIg vs placebo

Proportion of IVIg‐treated participants with an increase in disability during controlled IVIg withdrawal · people with multifocal motor neuropathy

IVIg probably leads to higher proportion of IVIg‐treated participants with an increase in… compared with placebo (moderate certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of IVIg‐treated participants with a decrease in muscle strength during controlled IVIg withdrawal · people with multifocal motor neuropathy

IVIg probably leads to lower proportion of IVIg‐treated participants with a decrease in muscle… compared with placebo (moderate certainty).

1 finding from 1 review

IVIg vs SCIg

Induction of labour · people with multifocal motor neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

IVIg vs SCIg

Adverse events · people with multifocal motor neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

IVIg vs SCIg

Proportion of participants with side effects attributable to treatment · people with multifocal motor neuropathy

It is very uncertain whether IVIg changes proportion of participants with side effects attributable to treatment compared with SCIg (very low certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with an improvement in disability scale used in the original study · people with multifocal motor neuropathy

IVIg showed no clear difference in proportion of participants with an improvement in disability scale… compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with an improvement of muscle strength · people with multifocal motor neuropathy

IVIg may leads to higher proportion of participants with an improvement of muscle strength compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with an improvement in disability at 12 months or later · people with multifocal motor neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

IVIg vs placebo

Proportion of participants in which at least 1 conduction block resolved after therapy · people with multifocal motor neuropathy

IVIg showed no clear difference in proportion of participants in which at least 1 conduction block… compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with side effects attributable to treatment · people with multifocal motor neuropathy

It is very uncertain whether IVIg changes proportion of participants with side effects attributable to treatment compared with placebo (very low certainty).

1 finding from 1 review

IVIg vs placebo

Seizure freedom · patients with drug‐resistant epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

IVIg vs placebo

Satisfactory seizure control 50% or greater reduction in seizure frequency for drug‐resistant epilepsy · patients with drug‐resistant epilepsy

IVIg showed no clear difference in satisfactory seizure control 50% or greater reduction in seizure… compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

All harmful effects · patients with drug‐resistant epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

IVIg vs placebo

Global assessment · patients with drug‐resistant epilepsy

IVIg may leads to higher global assessment compared with placebo (low certainty).

1 finding from 1 review