Question · asked by 1 review

IVIg vs prednisolone: Significant improvement in disability within 6 weeks

Population
people with CIDP
Intervention
IVIg
Comparison
prednisolone
Outcome
Significant improvement in disability within 6 weeks

Intravenous immunoglobulin showed no clear difference in significant improvement in disability within 6 weeks compared with prednisolone (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Intravenous immunoglobulin vs prednisolone
Significant improvement in disability within 6 weeks · patients with CIDP
Intravenous immunoglobulin showed no clear difference in significant improvement in disability within 6 weeks compared with prednisolone (moderate certainty).
Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy (2024) · Cochrane Headline outcomes only
RR 0.91 [0.5, 1.68]1 study · 29 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy
2024 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.