IVIg vs intravenous methylprednisolone: Significant improvement in disability within 6 weeks
- Population
- people with CIDP
- Intervention
- IVIg
- Comparison
- intravenous methylprednisolone
- Outcome
- Significant improvement in disability within 6 weeks
Intravenous immunoglobulin showed no clear difference in significant improvement in disability within 6 weeks compared with intravenous methylprednisolone (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Intravenous immunoglobulin vs intravenous methylprednisolone Significant improvement in disability within 6 weeks · people with CIDP Intravenous immunoglobulin showed no clear difference in significant improvement in disability within 6 weeks compared with intravenous methylprednisolone (moderate certainty). Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy (2024) · Cochrane Headline outcomes only | RR 1.46 [0.4, 5.38] | 1 study · 45 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy 2024 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- IVIg vs prednisolone · people with CIDP · 1 review
- IVIg vs plasma exchange · people with CIDP · 1 review
- IVIg vs placebo · people with CIDP · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.