Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

242 questions · 251 findings · 27 reviews

No studies found 44 · 17.5%GRADE not reported 3 · 1.2%Very low 69 · 27.5%Low 70 · 27.9%Moderate 52 · 20.7%High 13 · 5.2%

Psychological interventions (positive and negative reinforcement) vs no treatment

Sucking cessation (long term) · Children with a non-nutritive sucking habit (digit or pacifier)

Psychological interventions (positive and negative reinforcement) led to higher sucking cessation (long term) compared with no treatment; GRADE not reported.

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Loop ligation of myoma pseudocapsule plus vasopressin · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in loop ligation of myoma pseudocapsule plus vasopressin compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Fibrin sealant patch (collagen sponge with thrombin and fibrinogen) · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in fibrin sealant patch (collagen sponge with thrombin and fibrinogen) compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Misoprostol in abdominal myomectomy · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in misoprostol in abdominal myomectomy compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Misoprostol in laparoscopic myomectomy · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in misoprostol in laparoscopic myomectomy compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Bupivicaine plus epinephrine · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in bupivicaine plus epinephrine compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Intravenous injection of tranexamic acid · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in intravenous injection of tranexamic acid compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Gelatin‐thrombin matrix · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in gelatin‐thrombin matrix compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Dinoprostone (prostaglandin E2 analogue) · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in dinoprostone (prostaglandin E2 analogue) compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Taking adherence · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence showed no clear difference in taking adherence compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Dosing adherence · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence may leads to higher dosing adherence compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Timing adherence · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence showed no clear difference in timing adherence compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Drug holidays · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence showed no clear difference in drug holidays compared with standard care (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Adherence · solid organ transplant recipients

It is very uncertain whether interventions for increasing immunosuppressant medication adherence changes self‐reported adherence (proportion) compared with standard care (very low certainty).

2 findings from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Proportion of immunosuppressant trough concentration levels at target · solid organ transplant recipients

It is very uncertain whether interventions for increasing immunosuppressant medication adherence changes proportion of immunosuppressant trough concentration levels at target compared with standard care (very low certainty).

1 finding from 1 review