Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,183 questions · 2,385 findings · 241 reviews

No studies found 558 · 23.4%GRADE not reported 158 · 6.6%Very low 704 · 29.5%Low 618 · 25.9%Moderate 276 · 11.6%High 71 · 3%

Primary health professional‐ and community professional‐led interventions vs enhanced usual care

Clinical symptoms ‐ alcohol use (1 to 6 months post intervention) · adult patients with substance dependence

It is very uncertain whether primary health professional‐ and community professional‐led… changes clinical symptoms ‐ alcohol use (< 1 month post intervention) compared with enhanced usual care (very low certainty).

1 finding from 1 review

Primary health professional‐ and community professional‐led interventions vs enhanced usual care

Clinical symptoms ‐ drug use (< 1 month post intervention) ‐ heroin · adult patients with substance dependence

It is very uncertain whether primary health professional‐ and community professional‐led… changes clinical symptoms ‐ drug use (< 1 month post intervention) ‐ heroin compared with enhanced usual care (very low certainty).

1 finding from 1 review

Mindfulness‐based interventions (MBIs) vs non‐active comparators

Clinical CVD events (CVD mortality and non‐fatal MI) · people at high risk of or withcardiovascular disease

It is very uncertain whether mindfulness‐based interventions (MBIs) changes clinical CVD events (CVD mortality and non‐fatal MI) compared with non‐active comparators (very low certainty).

1 finding from 1 review