Findings

What do systematic reviews say?

3,024 questions · 3,338 findings · 330 reviews

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No studies found 735 · 22%GRADE not reported 282 · 8.4%Very low 962 · 28.8%Low 870 · 26.1%Moderate 384 · 11.5%High 105 · 3.1%

Multi‐component intervention vs no intervention

Proportion of participants with low back pain/discomfort · sedentary workers with musculoskeletal symptoms

Multi‐component intervention showed no clear difference in proportion of participants with low back pain/discomfort compared with no intervention (low certainty).

1 finding from 1 review

Workplace interventions for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers 2019 · Cochrane Headline outcomes only
RR 0.93 [0.69, 1.27]
3 studies · 107 participants
Low

Multi‐component intervention vs no intervention

Proportion of participants with upper back pain/discomfort · sedentary workers with musculoskeletal symptoms

Multi‐component intervention showed no clear difference in proportion of participants with upper back pain/discomfort compared with no intervention (low certainty).

1 finding from 1 review

Workplace interventions for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers 2019 · Cochrane Headline outcomes only
RR 0.88 [0.4, 1.96]
2 studies · 40 participants
Low

Multi‐component intervention vs no intervention

Proportion of participants with neck pain/discomfort · sedentary workers with musculoskeletal symptoms

Multi‐component intervention showed no clear difference in proportion of participants with neck pain/discomfort compared with no intervention (low certainty).

1 finding from 1 review

Workplace interventions for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers 2019 · Cochrane Headline outcomes only
RR 1 [0.76, 1.32]
3 studies · 115 participants
Low

Multi‐component intervention vs no intervention

Proportion of participants with shoulder pain/discomfort · sedentary workers with musculoskeletal symptoms

It is very uncertain whether multi‐component intervention changes proportion of participants with shoulder pain/discomfort compared with no intervention (very low certainty).

1 finding from 1 review

Workplace interventions for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers 2019 · Cochrane Headline outcomes only
RR 0.83 [0.12, 5.8]
2 studies · 66 participants
Very low

Pharmacological interventions vs no intervention

Insufficiency fractures and avascular necrosis · Adults undergoing pelvic radiotherapy

1 finding from 1 review

Pharmacological interventions for the prevention of insufficiency fractures and avascular necrosis associated with… 2018 · Cochrane Headline outcomes only
no estimate extracted
905 participants
Very low

Pharmacological interventions vs no intervention

BMD and fracture risk · Adults undergoing pelvic radiotherapy

1 finding from 1 review

Pharmacological interventions for the prevention of insufficiency fractures and avascular necrosis associated with… 2018 · Cochrane Headline outcomes only
no estimate extracted
905 participants
Very low

Pharmacological interventions vs no intervention

Bone turnover markers · Adults undergoing pelvic radiotherapy

1 finding from 1 review

Pharmacological interventions for the prevention of insufficiency fractures and avascular necrosis associated with… 2018 · Cochrane Headline outcomes only
no estimate extracted
905 participants
Very low

Pharmacological interventions vs no intervention

QoL · Adults undergoing pelvic radiotherapy

1 finding from 1 review

Pharmacological interventions for the prevention of insufficiency fractures and avascular necrosis associated with… 2018 · Cochrane Headline outcomes only
no estimate extracted
905 participants
Very low

Pharmacological interventions vs no intervention

All‐cause mortality · Adults undergoing pelvic radiotherapy

1 finding from 1 review

Pharmacological interventions for the prevention of insufficiency fractures and avascular necrosis associated with… 2018 · Cochrane Headline outcomes only
no estimate extracted
905 participants
Very low

Pharmacological interventions vs no intervention

Adverse events · Adults undergoing pelvic radiotherapy

1 finding from 1 review

Pharmacological interventions for the prevention of insufficiency fractures and avascular necrosis associated with… 2018 · Cochrane Headline outcomes only
no estimate extracted
905 participants
Very low

Multi‐component intervention vs no intervention

Mean difference in time spent sitting at work, short‐term · employees who sit at work

1 finding from 1 review

Workplace interventions for reducing sitting at work 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 573 participants
Very low

Multi‐component intervention vs no intervention

Mean difference in time in sitting bouts lasting 30 minutes or more, short‐term · employees who sit at work

1 finding from 1 review

Workplace interventions for reducing sitting at work 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 518 participants
Very low

SDAC + hospital intervention vs hospital intervention

Incidence and severity of symptoms of poisoning: incidence of need for intubation · first aid in patients with acute oral poisoning (not specified, tricyclic antidepressants, combinations of different drugs or yellow…

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 3562 participants
Very low

SDAC + hospital intervention vs hospital intervention

Duration of intubation · first aid in patients with acute oral poisoning (not specified, tricyclic antidepressants, combinations of different drugs or yellow…

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
Low

SDAC + hospital intervention vs hospital intervention

Drug absorption: cardenolide: AUC (µg/L × h) · first aid in patients with acute oral poisoning (not specified, tricyclic antidepressants, combinations of different drugs or yellow…

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 68 participants
Very low

SDAC + hospital intervention vs hospital intervention

Hospitalization · first aid in patients with acute oral poisoning (not specified, tricyclic antidepressants, combinations of different drugs or yellow…

It is very uncertain whether SDAC + hospital intervention changes incidence of hospitalization compared with hospital intervention alone (very low certainty).

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
RR 1.57 [1.22, 2.02]
1 study · 1479 participants
Very low

SDAC + hospital intervention vs hospital intervention

Incidence of admissions to the ICU · first aid in patients with acute oral poisoning (not specified, tricyclic antidepressants, combinations of different drugs or yellow…

It is very uncertain whether SDAC + hospital intervention changes incidence of ICU admission compared with hospital intervention alone (very low certainty).

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
RR 2.33 [1.42, 3.82]
1 study · 1479 participants
Very low

MDAC + hospital intervention vs SDAC + hospital intervention

Incidence of mortality · first aid in patients with acute oral poisoning (carbamazepine, yellow oleander, or combinations of different drugs)

It is very uncertain whether MDAC + hospital intervention changes incidence of mortality compared with SDAC + hospital intervention (very low certainty).

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
RR 0.59 [0.21, 1.63]
2 studies · 3476 participants
Very low

MDAC + hospital intervention vs SDAC + hospital intervention

Incidence of adverse events · first aid in patients with acute oral poisoning (carbamazepine, yellow oleander, or combinations of different drugs)

MDAC + hospital intervention may leads to higher incidence of adverse events compared with SDAC + hospital intervention (low certainty).

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
Peto OR 3.55 [1.85, 6.79]
2 studies · 3476 participants
Low

MDAC + hospital intervention vs SDAC + hospital intervention

Incidence and severity of symptoms of poisoning: incidence of need for intubation · first aid in patients with acute oral poisoning (carbamazepine, yellow oleander, or combinations of different drugs)

MDAC + hospital intervention showed no clear difference in incidence and severity of symptoms of poisoning: incidence of need… compared with SDAC + hospital intervention (low certainty).

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
RR 1.01 [0.75, 1.38]
2 studies · 3097 participants
Low