Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

251 questions · 277 findings · 23 reviews

No studies found 64 · 23.1%GRADE not reported 13 · 4.7%Very low 131 · 47.3%Low 59 · 21.3%Moderate 7 · 2.5%High 3 · 1.1%

Pharmacological interventions vs placebo

acceptability ‐ drop‐outs due to adverse events: post‐intervention · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to adverse events: post‐intervention compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Acceptability · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to any cause: post‐intervention compared with placebo (very low certainty).

2 findings from 1 review

Pharmacological interventions vs placebo

Incidence of depression ‐ post‐intervention: 0 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes incidence of depression ‐ post‐intervention: 0 months compared with placebo (very low certainty).

1 finding from 1 review