What do systematic reviews say?

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in loop ligation of myoma pseudocapsule plus vasopressin compared with placebo or no treatment (low certainty).

• Interventions to reduce haemorrhage during myomectomy for fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 70 participants
  Low

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in fibrin sealant patch (collagen sponge with thrombin and fibrinogen) compared with placebo or no treatment (low certainty).

• Interventions to reduce haemorrhage during myomectomy for fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 70 participants
  Low

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in misoprostol in abdominal myomectomy compared with placebo or no treatment (moderate certainty).

• Interventions to reduce haemorrhage during myomectomy for fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 25 participants
  Moderate

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in misoprostol in laparoscopic myomectomy compared with placebo or no treatment (moderate certainty).

• Interventions to reduce haemorrhage during myomectomy for fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 64 participants
  Moderate

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in vasopressin compared with placebo or no treatment (moderate certainty).

• Interventions to reduce haemorrhage during myomectomy for fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 128 participants
  Moderate

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in bupivicaine plus epinephrine compared with placebo or no treatment (low certainty).

• Interventions to reduce haemorrhage during myomectomy for fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Low

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in intravenous injection of tranexamic acid compared with placebo or no treatment (low certainty).

• Interventions to reduce haemorrhage during myomectomy for fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Low

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in gelatin‐thrombin matrix compared with placebo or no treatment (low certainty).

• Interventions to reduce haemorrhage during myomectomy for fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Low

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in ascorbic acid compared with placebo or no treatment (low certainty).

• Interventions to reduce haemorrhage during myomectomy for fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 102 participants
  Low

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in dinoprostone (prostaglandin E2 analogue) compared with placebo or no treatment (low certainty).

• Interventions to reduce haemorrhage during myomectomy for fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 108 participants
  Low

Dietary interventions vs diet and physical activity interventions combined

• Interventions for preventing obesity in children 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 3971 participants
  High

Dietary interventions vs diet and physical activity interventions combined

• Interventions for preventing obesity in children 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 3971 participants
  High

Family interventions vs no intervention

Family interventions probably leads to lower new smoking at compared with no intervention (moderate certainty).

• Family‐based programmes for preventing smoking by children and adolescents 2015 · Cochrane Headline outcomes only
  RR 0.76 [0.68, 0.84]
  9 studies · 48102 participants
  Moderate

Self‐management interventions vs usual care

It is very uncertain whether self‐management interventions changes respiratory‐related hospital admissions compared with usual care (very low certainty).

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  OR 0.75 [0.57, 0.98]
  3263 participants
  Very low
• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  OR 0.69 [0.51, 0.94]
  14 studies · 3157 participants
  Moderate

Self‐management interventions vs usual care

Self‐management interventions showed no clear difference in respiratory‐related mortality compared with usual care (low certainty).

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  OR 1.7 [0.89, 3.26]
  1572 participants
  Low
• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  OR 1.94 [1.2, 3.13]
  7 studies · 1219 participants
  Very low

Self‐management interventions vs usual care

Self‐management interventions showed no clear difference in all‐cause mortality compared with usual care (low certainty).

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  OR 0.86 [0.59, 1.26]
  5719 participants
  Low
• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  OR 1.06 [0.71, 1.59]
  16 studies · 3296 participants
  Moderate

Self‐management interventions vs usual care

Self‐management interventions showed no clear difference in all‐cause hospital admissions compared with usual care (moderate certainty).

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  OR 0.88 [0.71, 1.08]
  2633 participants
  Moderate
• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  OR 0.74 [0.54, 1.03]
  10 studies · 2467 participants
  Moderate

Self‐management interventions vs usual care

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1401 participants
  Moderate
• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 740 participants
  Moderate

Self‐management interventions vs usual care

• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 1582 participants
  High

Self‐management interventions vs usual care

• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 217 participants
  Low