Findings

What do systematic reviews say?

47 questions · 47 findings · 8 reviews

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No studies found 2 · 4.3%GRADE not reported 4 · 8.5%Very low 12 · 25.5%Low 23 · 48.9%Moderate 6 · 12.8%High 0 · 0%

Inhaled corticosteroids vs placebo

Quality of life: Quality of Well Being score change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Inhaled corticosteroids for cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 23 participants
Low

Inhaled corticosteroids vs placebo

Adverse effects · adults and children with cystic fibrosis

1 finding from 1 review

Inhaled corticosteroids for cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 295 participants
Low

A boost of inhaled corticosteroids vs usual care

Exacerbations · autumn asthma exacerbations in children

A boost of inhaled corticosteroids showed no clear difference in exacerbations compared with usual care (moderate certainty).

1 finding from 1 review

Interventions for autumn exacerbations of asthma in children 2018 · Cochrane Headline outcomes only
OR 0.86 [0.32, 2.3]
1 study · 173 participants
Moderate

A boost of inhaled corticosteroids vs usual care

Adverse events · autumn asthma exacerbations in children

A boost of inhaled corticosteroids showed no clear difference in adverse events compared with usual care (moderate certainty).

1 finding from 1 review

Interventions for autumn exacerbations of asthma in children 2018 · Cochrane Headline outcomes only
OR 0.67 [0.34, 1.33]
1 study · 176 participants
Moderate

Effects of different inhaled corticosteroids on growth in children with persistent asthma: fluticasone vs beclomethasone

Linear growth velocity (cm/year) · children up to 18 years of age with persistent asthma

Effects of different inhaled corticosteroids on growth in children… may leads to higher linear growth velocity (cm/year) compared with beclomethasone (low certainty).

1 finding from 1 review

Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth 2019 · Cochrane Headline outcomes only
MD 0.81 [0.46, 1.16]
1 study · 23 participants
Low

Effects of different inhaled corticosteroids on growth in children with persistent asthma: fluticasone vs budesonide

Linear growth velocity (cm/year) · children up to 18 years of age with persistent asthma

It is very uncertain whether effects of different inhaled corticosteroids on growth in children… changes linear growth velocity (cm/year) compared with budesonide (very low certainty).

1 finding from 1 review

Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth 2019 · Cochrane Headline outcomes only
MD 0.39
2 studies · 236 participants
Very low

Effects of different inhaled corticosteroids on growth in children with persistent asthma: fluticasone vs budesonide

Change in height · children up to 18 years of age with persistent asthma

Effects of different inhaled corticosteroids on growth in children… probably leads to higher change in height (cm) over a period of time compared with budesonide (moderate certainty).

1 finding from 1 review

Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth 2019 · Cochrane Headline outcomes only
MD 0.97 [0.62, 1.32]
2 studies · 359 participants
Moderate