Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

17 questions · 18 findings · 3 reviews

No studies found 0 · 0%GRADE not reported 3 · 16.7%Very low 5 · 27.8%Low 3 · 16.7%Moderate 7 · 38.9%High 0 · 0%

GnRH antagonist vs long‐course GnRH agonist

Cycle cancellation due to poor ovarian response · women undergoing assisted reproductive technology (ART)

GnRH antagonist probably leads to higher cycle cancellation due to poor ovarian response compared with long‐course GnRH agonist (moderate certainty).

1 finding from 1 review

Gonadotropins with GnRH antagonist vs gonadotropins alone

Live birth rate per couple · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether gonadotropins with GnRH antagonist changes live birth rate per couple compared with gonadotropins alone (very low certainty).

1 finding from 1 review

Gonadotropins with GnRH antagonist vs gonadotropins alone

Multiple pregnancy rate · intrauterine insemination (IUI) in women with infertility

Gonadotropins with GnRH antagonist showed no clear difference in multiple pregnancy rate per couple compared with gonadotropins alone (moderate certainty).

1 finding from 1 review

Gonadotropins with GnRH antagonist vs gonadotropins alone

Clinical pregnancy rate · intrauterine insemination (IUI) in women with infertility

Gonadotropins with GnRH antagonist showed no clear difference in clinical pregnancy rate per couple compared with gonadotropins alone (low certainty).

1 finding from 1 review

Gonadotropins with GnRH antagonist vs gonadotropins alone

Ectopic pregnancy rate per couple · intrauterine insemination (IUI) in women with infertility

Gonadotropins with GnRH antagonist showed no clear difference in ectopic pregnancy rate per couple compared with gonadotropins alone (low certainty).

1 finding from 1 review

GnRH agonist‐antagonist cotreatment plus chemotherapy vs chemotherapy alone

Pregnancy · premenopausal women with malignant conditions, receiving GnRH agonist before or in parallel to chemotherapy

It is very uncertain whether gnRH agonist‐antagonist cotreatment plus chemotherapy changes pregnancy compared with chemotherapy alone (very low certainty).

1 finding from 1 review

GnRH agonist‐antagonist cotreatment plus chemotherapy vs chemotherapy alone

Menstruation recovery or maintenance: · premenopausal women with malignant conditions, receiving GnRH agonist before or in parallel to chemotherapy

It is very uncertain whether gnRH agonist‐antagonist cotreatment plus chemotherapy changes menstruation recovery or maintenance: compared with chemotherapy alone (very low certainty).

2 findings from 1 review