Question · asked by 1 review

Gonadotropins with GnRH antagonist vs gonadotropins alone: Live birth rate per couple

It is very uncertain whether gonadotropins with GnRH antagonist changes live birth rate per couple compared with gonadotropins alone (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Gonadotropins with GnRH antagonist vs gonadotropins alone
Live birth rate per couple · intrauterine insemination (IUI) in women with infertility
It is very uncertain whether gonadotropins with GnRH antagonist changes live birth rate per couple compared with gonadotropins alone (very low certainty).
Agents for ovarian stimulation for intrauterine insemination (IUI) in ovulatory women with infertility (2021) · Cochrane Headline outcomes only
OR 1.5 [0.52, 4.39]3 studies · 419 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Agents for ovarian stimulation for intrauterine insemination (IUI) in ovulatory women with infertility
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.