Caesarean section · women with prelabour rupture of membranes at term (37 weeks' gestation or later)
Planned early birth showed no clear difference in caesarean section compared with expectant management (low certainty).
1 finding from 1 review
Serious maternal morbidity or death · women with prelabour rupture of membranes at term (37 weeks' gestation or later)
1 finding from 1 review
Perinatal mortality · women with prelabour rupture of membranes at term (37 weeks' gestation or later)
Planned early birth showed no clear difference in perinatal mortality (stillbirth or neonatal mortality) compared with expectant management (moderate certainty).
1 finding from 1 review
Relative abundance of Veillonella spp. · Children under 6 years with severe early childhood caries and caries-free controls
Veillonella spp. mean relative abundance was lower in the S-ECC group; no comparative effect estimate or CI was reported.
1 finding from 1 review
Relative abundance of S. mutans in saliva · Children under 6 years with severe early childhood caries and caries-free controls
S. mutans median relative abundance was higher in the S-ECC group, without a comparative effect estimate or CI.
1 finding from 1 review
Streptococcus relative abundance · Children under 6 years with severe early childhood caries and caries-free controls
Streptococcus mean relative abundance was slightly higher in the S-ECC group; no comparative effect estimate or CI was reported.
1 finding from 1 review
Veillonella spp. and Streptococcus mutans interaction · Children under 6 years with severe early childhood caries and caries-free controls
The study reported a possible role for Veillonella spp. in supporting cariogenic species, without a quantitative effect estimate.
1 finding from 1 review
Veillonella spp. may promote proliferation or survival of cariogenic species, as shown for interactions between Veillonella spp. and S. mutans.
1 study · 82 participants
GRADE not reported
Veillonella dispar relative abundance · Children under 6 years with severe early childhood caries and caries-free controls
Veillonella dispar median relative abundance was higher in the S-ECC group, without a comparative effect estimate or CI.
1 finding from 1 review
Chronic lung disease · preterm infants
Very early treatment showed no clear difference in chronic lung disease compared with expectant management (low certainty).
1 finding from 1 review
Severe intraventricular hemorrhage in infants who received neuroimaging · preterm infants
Very early treatment showed no clear difference in severe Intraventricular hemorrhage (grades III and IV) compared with expectant management (moderate certainty).
1 finding from 1 review
NEC ≥ stage II · preterm infants
Very early treatment showed no clear difference in necrotizing enterocolitis (NEC; stage 2 or greater) compared with expectant management (moderate certainty).
1 finding from 1 review
Duration of hospitalization · preterm infants
1 finding from 1 review
Neurodevelopmental outcomes (moderate/severe cognitive delay at 18 to 24 months) · preterm infants
Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe cognitive delay at 18… compared with expectant management (low certainty).
1 finding from 1 review
Neurodevelopmental outcomes (moderate/severe motor delay at 18 to 24 months) · preterm infants
Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe motor delay at 18 to 24… compared with expectant management (low certainty).
1 finding from 1 review
Neurodevelopmental outcomes (moderate/severe language delay at 18 to 24 months) · preterm infants
Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe language delay at 18 to… compared with expectant management (low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay · preterm infants
Very early treatment showed no clear difference in all‐cause mortality during hospital stay compared with expectant management (moderate certainty).
1 finding from 1 review
Proportion of infants requiring surgical PDA ligation or transcatheter occlusion · preterm infants
Very early treatment showed no clear difference in proportion of infants requiring surgical PDA ligation or… compared with expectant management (moderate certainty).
1 finding from 1 review
Proportion of infants receiving any pharmacotherapy for a hemodynamically significant PDA · preterm infants
It is very uncertain whether very early treatment changes proportion of infants receiving any pharmacotherapy for a… compared with expectant management (very low certainty).
1 finding from 1 review
Maternal mortality or morbidity · pregnant women with hypertensive disorders from 34 weeks' gestation to term
Planned early delivery leads to lower composite maternal mortality and morbidity compared with expectant management (high certainty).
1 finding from 1 review
Composite infant mortality and morbidity · pregnant women with hypertensive disorders from 34 weeks' gestation to term
1 finding from 1 review