Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 7 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 7 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Down syndrome vs Individuals without Down syndrome (healthy controls: siblings, schoolchildren or others)

Mean DMFT (decayed, missing, filled permanent teeth) · Individuals of all ages

Individuals with Down syndrome had a lower mean DMFT in permanent teeth than controls (pooled SMD -0.18, 95% CI -0.35 to -0.02; 6 studies; I2=20%); certainty of evidence not graded.

1 finding from 1 review

Down syndrome vs Individuals without Down syndrome (healthy controls: siblings, schoolchildren or others)

Dental caries · Individuals of all ages

Individuals with Down syndrome had a lower prevalence of dental caries than those without (pooled OR 0.36, 95% CI 0.22 to 0.57; 2 studies; I2=0%); certainty of evidence not graded.

1 finding from 1 review

Down syndrome (oral health status) vs Healthy controls

Oral health status (caries, DMFT, calculus, erosion, malocclusion, treatment indices) · Children with Down syndrome in Dubai

One study found children with Down syndrome had similar caries prevalence but higher DMFT, calculus, erosion and malocclusion than controls, with better restorative-care access (narrative synthesis; not GRADE-rated).

1 finding from 1 review