Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy
Chlorhexidine showed no clear difference in oral candidiasis (present) compared with chlorhexidine plus nystatin; GRADE not reported.
1 finding from 1 review
Reduction in level of contamination in aerosols (CFU): chlorhexidine coolant vs distilled water during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether chlorhexidine coolant changes reduction in level of contamination in aerosols (CFU): chlorhexidine… compared with distilled water coolant (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine gel 1% showed no clear difference in presence of dry socket compared with chlorhexidine gel 0.2%; GRADE not reported.
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
Chlorhexidine showed no clear difference in incidence of VAP compared with potassium permanganate; GRADE not reported.
1 finding from 1 review
RR 0.87 [0.50, 1.52]
2 studies
GRADE not reported
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Chlorhexidine showed no clear difference in mortality compared with potassium permanganate; GRADE not reported.
1 finding from 1 review
RR 1.11 [0.89, 1.38]
2 studies
GRADE not reported
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Chlorhexidine showed no clear difference in oral mucositis (any severity) compared with placebo/no treatment (low certainty).
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Chlorhexidine showed no clear difference in oral mucositis (any severity) compared with cryotherapy (ice chips); GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Chlorhexidine showed no clear difference in oral mucositis (moderate to severe) compared with cryotherapy (ice chips); GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Chlorhexidine showed no clear difference in oral mucositis (severe) compared with placebo/no treatment (low certainty).
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Chlorhexidine showed no clear difference in oral mucositis (severe) compared with cryotherapy (ice chips); GRADE not reported.
1 finding from 1 review
Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy
Chlorhexidine showed no clear difference in oral candidiasis (present) compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy
Chlorhexidine showed no clear difference in oral candidiasis (present) compared with nystatin; GRADE not reported.
1 finding from 1 review
Chlorhexidine spray vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether tempered chlorhexidine changes reduction in level of contamination by particles >5 um (droplets) at… compared with non-tempered chlorhexidine (very low certainty).
3 findings from 1 review
MD -10.8 [-15.15, -6.45]
1 study · 20 participants
Very low
MD -17.6 [-23.7, -11.5]
1 study · 20 participants
Very low
MD -15.8 [-22.67, -8.93]
1 study · 20 participants
Very low
Reduction in level of contamination in aerosols (CFU): chlorhexidine vs povidone iodine coolant during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether antimicrobial coolant A (chlorhexidine) changes reduction in level of contamination in aerosols (CFU): chlorhexidine… compared with antimicrobial coolant B (povidone iodine) (very low certainty).
1 finding from 1 review