Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

80 questions · 80 findings · 7 reviews

No studies found 8 · 10%GRADE not reported 9 · 11.3%Very low 19 · 23.8%Low 14 · 17.5%Moderate 19 · 23.8%High 11 · 13.8%

Bisphosphonates vs placebo

Number of participants who experienced side effects related to use of bisphosphonates · Paget's disease of bone

Bisphosphonates showed no clear difference in number of participants who experienced side effects related to use… compared with placebo (low certainty).

1 finding from 1 review