Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

98 questions · 102 findings · 13 reviews

No studies found 10 · 9.8%GRADE not reported 1 · 1%Very low 16 · 15.7%Low 45 · 44.1%Moderate 25 · 24.5%High 5 · 4.9%

Perioperative beta‐blockers vs placebo or usual care

Ventricular arrhythmias (within 30 days) · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)

It is very uncertain whether perioperative beta‐blockers changes ventricular arrhythmias (within 30 days) compared with placebo or standard care (very low certainty).

1 finding from 1 review

Perioperative beta‐blockers vs placebo or usual care

Atrial fibrillation or atrial flutter, or both (within 30 days) · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)

Perioperative beta‐blockers may leads to lower atrial fibrillation or atrial flutter, or both (within 30 days) compared with placebo or standard care (low certainty).

1 finding from 1 review

Perioperative beta‐blockers vs placebo or usual care

Bradycardia · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)

Perioperative beta‐blockers may leads to higher bradycardia (within 30 days; as defined by study authors, minimum… compared with placebo or standard care (low certainty).

1 finding from 1 review

Perioperative beta‐blockers vs placebo or usual care

Hypotension · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)

Perioperative beta‐blockers probably leads to higher hypotension (within 30 days; as defined by study authors, minimum… compared with placebo or standard care (moderate certainty).

1 finding from 1 review

Systemic administration of beta‐blockers vs placebo or no treatment

Rescue treatment with anti‐VEGF agents · Prevention of retinopathy of prematurity in preterm infants

Systemic administration of beta‐blockers may leads to lower rescue treatment with anti‐VEGF agents compared with placebo or no treatment (low certainty).

1 finding from 1 review

Systemic administration of beta‐blockers vs placebo or no treatment

Treatment with laser photocoagulation or cryotherapy · Prevention of retinopathy of prematurity in preterm infants

Systemic administration of beta‐blockers may leads to lower treatment with laser photocoagulation or cryotherapy compared with placebo or no treatment (low certainty).

1 finding from 1 review

Systemic administration of beta‐blockers vs placebo or no treatment

Progression to stage 2 with plus disease · Prevention of retinopathy of prematurity in preterm infants

Systemic administration of beta‐blockers showed no clear difference in progression to stage 2 with plus disease compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Systemic administration of beta‐blockers vs placebo or no treatment

Progression to stage 3 ROP · Prevention of retinopathy of prematurity in preterm infants

Systemic administration of beta‐blockers probably leads to lower progression to stage 3 ROP compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Systemic administration of beta‐blockers vs placebo or no treatment

Progression to stage 4 or 5 ROP · Prevention of retinopathy of prematurity in preterm infants

Systemic administration of beta‐blockers showed no clear difference in progression to stage 4 or 5 ROP compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Systemic administration of beta‐blockers vs placebo or no treatment

Arterial hypotension and/or bradycardia requiring treatment · Prevention of retinopathy of prematurity in preterm infants

Systemic administration of beta‐blockers may leads to higher arterial hypotension and/or bradycardia requiring treatment compared with placebo or no treatment (low certainty).

1 finding from 1 review