Question · asked by 1 review

Systemic administration of beta‐blockers vs placebo or no treatment: Progression to stage 2 with plus disease

Systemic administration of beta‐blockers showed no clear difference in progression to stage 2 with plus disease compared with placebo or no treatment (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Systemic administration of beta‐blockers vs placebo or no treatment
Progression to stage 2 with plus disease · Prevention of retinopathy of prematurity in preterm infants
Systemic administration of beta‐blockers showed no clear difference in progression to stage 2 with plus disease compared with placebo or no treatment (moderate certainty).
Beta‐blockers for prevention and treatment of retinopathy of prematurity in preterm infants (2018) · Cochrane Headline outcomes only
RR 0.25 [0.03, 2.16]2 studies · 161 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Beta‐blockers for prevention and treatment of retinopathy of prematurity in preterm infants
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.