Repetition of SH at post‐intervention · self‐harm in adults
It is very uncertain whether newer generation antidepressants (NGAs) changes repetition of SH by post‐intervention (NGA class)№ of participants:… compared with placebo (very low certainty).
3 findings from 1 review
OR 0.59 [0.29, 1.19]
Studies not reported
Very low
OR 0.67 [0.18, 2.41]
Studies not reported
Very low
OR 0.55 [0.24, 1.29]
Studies not reported
Low
Outcomes (2‐6 months post‐treatment) · adults with panic disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Failure to respond at endpoint (6‐12 weeks) · adults with panic disorder
Antidepressants may leads to lower failure to respond compared with placebo (low certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
Antidepressants probably leads to lower total number of dropouts compared with placebo (moderate certainty).
1 finding from 1 review
Failure to remit at endpoint · adults with panic disorder
Antidepressants probably leads to lower failure to remit compared with placebo (moderate certainty).
1 finding from 1 review
panic symptoms · adults with panic disorder
2 findings from 1 review
Withdrawals due to adverse events · adults with panic disorder
Antidepressants probably leads to higher number of dropouts due to adverse effects compared with placebo (moderate certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
Tricyclic antidepressants probably leads to lower total number of dropouts compared with placebo (moderate certainty).
1 finding from 1 review
Failure to remit at endpoint · adults with panic disorder
Tricyclic antidepressants may leads to lower failure to remit compared with placebo (low certainty).
1 finding from 1 review
panic symptoms · adults with panic disorder
2 findings from 1 review
Withdrawals due to adverse events · adults with panic disorder
Tricyclic antidepressants probably leads to higher number of dropouts due to adverse effects compared with placebo (moderate certainty).
1 finding from 1 review
Outcomes (2‐6 months post‐treatment) · adults with panic disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Failure to respond at endpoint (6‐12 weeks) · adults with panic disorder
Tricyclic antidepressants probably leads to lower failure to respond compared with placebo (moderate certainty).
1 finding from 1 review
Efficacy as a continuous outcome · adults with cancer and depression
1 finding from 1 review
Efficacy as a dichotomous outcome · adults with cancer and depression
It is very uncertain whether antidepressants changes efficacy as a dichotomous outcome compared with placebo (very low certainty).
1 finding from 1 review
Acceptability ‐ total dropouts · adults with cancer and depression
It is very uncertain whether antidepressants changes dropouts due to any cause (acceptability) compared with placebo (very low certainty).
1 finding from 1 review
Irritability · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…
1 finding from 1 review
Aggression · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…
Antidepressants may leads to higher adverse effects compared with placebo (low certainty).
1 finding from 1 review
Gambling symptom severity · treatment of disordered and problem gambling
1 finding from 1 review