Resolution of ear discharge ‐ measured after 4 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
It is very uncertain whether systemic antibiotics changes resolution of ear discharge ‐ measured after 4 weeks (4 weeks)… compared with no treatment or placebo on top of topical antibiotics (very low certainty).
2 findings from 1 review
Appendectomy in the antibiotic group · adults with uncomplicated appendicitis
1 finding from 1 review
Adverse effects of antibiotics · prolonged wet cough in children
Antibiotics showed no clear difference in children experiencing adverse effects of antibiotics (e.g.… compared with placebo (low certainty).
1 finding from 1 review
Need for additional antibiotic therapy · women with management of intra‐amniotic infection
1 finding from 1 review
Need for additional antibiotic therapy · women with management of intra‐amniotic infection
1 finding from 1 review
Antibiotic resistance · people presenting for surgery where healing of surgical wound planned to be by primary intention
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women
Antibiotics showed no clear difference in incidence of mastitis within 6 months postpartum ‐ Antibiotics… compared with topical treatments (low certainty).
2 findings from 1 review
Surgical site infection · solid organ transplant recipients
It is very uncertain whether antibiotics changes surgical site infections* Time frame: 2 to 6 weeks compared with no antibiotics (very low certainty).
1 finding from 1 review
Death (any case) Time frame: 2 to 4 weeks · solid organ transplant recipients
It is very uncertain whether antibiotics changes death (any case) Time frame: 2 to 4 weeks compared with no antibiotics (very low certainty).
1 finding from 1 review
Graft loss including death · solid organ transplant recipients
It is very uncertain whether antibiotics changes graft loss (including death with functioning graft) Time frame: 2… compared with no antibiotics (very low certainty).
1 finding from 1 review
UTI · solid organ transplant recipients
It is very uncertain whether antibiotics changes other infection: UTI Time frame: 2 to 6 weeks compared with no antibiotics (very low certainty).
1 finding from 1 review
Other infection: septicaemia Time frame: 2 to 6 weeks · solid organ transplant recipients
It is very uncertain whether antibiotics changes other infection: septicaemia Time frame: 2 to 6 weeks compared with no antibiotics (very low certainty).
1 finding from 1 review
Other infection: pneumonia Time frame: 30 days · solid organ transplant recipients
It is very uncertain whether antibiotics changes other infection: pneumonia Time frame: up to 6 weeks compared with no antibiotics (very low certainty).
1 finding from 1 review
Adverse drug reactions · solid organ transplant recipients
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbations · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics probably leads to lower number of people with one or more exacerbations WMD of compared with placebo (moderate certainty).
1 finding from 1 review
Annual Exacerbation Rates · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics probably leads to lower rate of exacerbation per patient/year WMD of compared with placebo (moderate certainty).
1 finding from 1 review
HRQoL: total score · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
1 finding from 1 review
All‐cause mortality WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics showed no clear difference in all‐cause mortality WMD of compared with placebo (moderate certainty).
1 finding from 1 review
Serious adverse events WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics showed no clear difference in serious adverse events WMD of compared with placebo (moderate certainty).
1 finding from 1 review
Any adverse event WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics showed no clear difference in any adverse event WMD of compared with placebo (moderate certainty).
1 finding from 1 review