Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

294 questions · 308 findings · 41 reviews

No studies found 65 · 21.1%GRADE not reported 21 · 6.8%Very low 83 · 26.9%Low 66 · 21.4%Moderate 47 · 15.3%High 26 · 8.4%

Antibiotics vs placebo

Total postoperative infections ‐ early and late · women having elective vaginal hysterectomy

Antibiotics may leads to lower total postoperative infections ‐ early and late compared with placebo (low certainty).

1 finding from 1 review

Antibiotics vs placebo

Pelvic infection · women having elective abdominal hysterectomy

Antibiotics probably leads to lower pelvic infection compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo

Other serious infections · women having elective abdominal hysterectomy

It is very uncertain whether antibiotics changes other serious infections compared with placebo (very low certainty).

1 finding from 1 review

Antibiotics vs placebo

Postoperative fever · women having elective abdominal hysterectomy

Antibiotics probably leads to lower postoperative fever compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo

Total adverse effects · women having elective abdominal hysterectomy

It is very uncertain whether antibiotics changes total adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Antibiotics vs placebo

Urinary tract infection · women having elective vaginal hysterectomy

Antibiotics probably leads to lower urinary tract infection compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo

Other serious infections · women having elective vaginal hysterectomy

It is very uncertain whether antibiotics changes other serious infections compared with placebo (very low certainty).

1 finding from 1 review

Antibiotics vs placebo

Postoperative fever · women having elective vaginal hysterectomy

Antibiotics probably leads to lower postoperative fever compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo

Total postoperative infections ‐ early and late · women having elective abdominal hysterectomy

Antibiotics may leads to lower total postoperative infections ‐ early and late compared with placebo (low certainty).

1 finding from 1 review

Antibiotics vs placebo

Abdominal surgical site infection · women having elective abdominal hysterectomy

Antibiotics probably leads to lower abdominal wound infection compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo

Urinary tract infection · women having elective abdominal hysterectomy

Antibiotics probably leads to lower urinary tract infection compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Number of participants who were not cured at · children < 24 months with ongoing symptoms (cough/wheeze) post‐acute bronchiolitis

Antibiotics showed no clear difference in number of participants who were not cured at compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Number of participants rehospitalised for a respiratory illness · children < 24 months with ongoing symptoms (cough/wheeze) post‐acute bronchiolitis

Antibiotics showed no clear difference in number of participants rehospitalised for a respiratory illness compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Proportion of participants with recurrent wheeze · children < 24 months with ongoing symptoms (cough/wheeze) post‐acute bronchiolitis

Antibiotics showed no clear difference in proportion of participants with recurrent wheeze compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antibiotics vs placebo, no treatment or therapy of unproven effectiveness

Complete resolution of OME at 2 to 3 months · Children with otitis media with effusion

Antibiotics probably leads to higher complete resolution of OME at 2 to 3 months compared with placebo, no treatment or therapy of unproven effectiveness (moderate certainty).

2 findings from 1 review

Antibiotics vs placebo, no treatment or therapy of unproven effectiveness

Complete resolution of OME at more than 6 months · Children with otitis media with effusion

Antibiotics may leads to higher complete resolution of OME at more than 6 months compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).

1 finding from 1 review