Findings

What do systematic reviews say?

594 questions · 624 findings · 70 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 151 · 24.2%GRADE not reported 53 · 8.5%Very low 174 · 27.9%Low 129 · 20.7%Moderate 82 · 13.1%High 35 · 5.6%

Antibiotics vs no treatment or placebo on top of topical antibiotics

Hearing · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antibiotics

Serious complications ‐ measured at 19 to 24 days · people (of any age) with CSOM

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Antibiotics vs no treatment or placebo on top of topical antibiotics

Suspected ototoxicity · people (of any age) with CSOM

It is very uncertain whether systemic antibiotics changes suspected ototoxicity ‐ measured at 10 days to 3 weeks compared with no treatment or placebo on top of topical antibiotics (very low certainty).

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
RR 3 [0.13, 71.92]
3 studies · 250 participants
Very low

Antibiotics vs no treatment or placebo on top of topical antibiotics

Resolution of ear discharge ‐ measured at 1 to 2 weeks · people (of any age) with CSOM

Systemic antibiotics showed no clear difference in resolution of ear discharge ‐ measured at 1 to 2 weeks compared with no treatment or placebo on top of topical antibiotics (low certainty).

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
RR 1.02 [0.93, 1.12]
5 studies · 390 participants
Low

Antibiotics vs no treatment or placebo on top of topical antibiotics

Resolution of ear discharge ‐ measured after 4 weeks · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics after D&C vs D&C during antibiotics

Absence of fever (degree‐hour) ‐ Clindamycin after D&C versus D&C during clindamycin · patients with treating septic abortion

1 finding from 1 review

Antibiotics for treating septic abortion 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 37 participants
Moderate

Antibiotics after D&C vs D&C during antibiotics

Absence of fever (degree‐hour) ‐ Penicillin + chloramphenicol after D&C versus D&C during penicillin + chloramphenicol therapy) · patients with treating septic abortion

1 finding from 1 review

Antibiotics for treating septic abortion 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Moderate

Nebulised antibiotics vs IV antibiotics

FVC (% predicted) Change from baseline · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

1 finding from 1 review

Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 54 participants
Very low

Nebulised antibiotics vs IV antibiotics

Time to next exacerbation · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nebulised antibiotics vs IV antibiotics

Quality of life · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: anti‐pseudomonal antibiotics vs placebo

Antibiotic resistance: frequency of tobramycin‐resistant P aeruginosa · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

Summary of findings: anti‐pseudomonal antibiotics showed no clear difference in antibiotic resistance: frequency of tobramycin‐resistant P aeruginosa compared with placebo (moderate certainty).

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
RR 1.95 [0.86, 4.42]
2 studies · 672 participants
Moderate

Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

Development of antibiotic resistance · patients on maintenance HD with CRBSI

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating catheter‐related bloodstream infections in people receiving maintenance haemodialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo or no treatment

Fever ‐ not measured · Women undergoing operative vaginal delivery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for operative vaginal delivery 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo or no treatment

Length of maternal hospital stay (days) · Women undergoing operative vaginal delivery

1 finding from 1 review

Antibiotic prophylaxis for operative vaginal delivery 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Antibiotics vs placebo or no treatment

Infected episiotomy/laceration (superficial perineal wound infection) № of participants: 3420 (1 RCT) · Women undergoing operative vaginal delivery

Any antibiotics leads to lower infected episiotomy/laceration (superficial perineal wound… compared with placebo or no treatment (high certainty).

1 finding from 1 review

Antibiotic prophylaxis for operative vaginal delivery 2020 · Cochrane Headline outcomes only
RR 0.53 [0.4, 0.69]
Studies not reported
High

Antibiotics vs placebo or no treatment

Infected episiotomy/laceration (deep perineal wound infection № of participants: 3420 (1 RCT) · Women undergoing operative vaginal delivery

Any antibiotics leads to lower infected episiotomy/laceration (deep perineal wound infection № of… compared with placebo or no treatment (high certainty).

1 finding from 1 review

Antibiotic prophylaxis for operative vaginal delivery 2020 · Cochrane Headline outcomes only
RR 0.46 [0.31, 0.69]
Studies not reported
High

Antibiotics vs placebo or no treatment

Infected episiotomy/laceration (organ or space infection) № of participants: 3420 (1 RCT) · Women undergoing operative vaginal delivery

Any antibiotics showed no clear difference in infected episiotomy/laceration (organ or space infection) № of… compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antibiotic prophylaxis for operative vaginal delivery 2020 · Cochrane Headline outcomes only
RR 0.11 [0.01, 2.05]
Studies not reported
Low

Antibiotics vs placebo or no treatment

Infected episiotomy/laceration (wound breakdown) № of participants: 2593 (1 RCT) · Women undergoing operative vaginal delivery

Any antibiotics probably leads to lower infected episiotomy/laceration (wound breakdown) № of participants:… compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for operative vaginal delivery 2020 · Cochrane Headline outcomes only
RR 0.52 [0.43, 0.63]
Studies not reported
Moderate

Antibiotics vs placebo or no treatment

Endometritis · Women undergoing operative vaginal delivery

Any antibiotics showed no clear difference in endometritis № of participants: 3813 (2 RCTs) compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antibiotic prophylaxis for operative vaginal delivery 2020 · Cochrane Headline outcomes only
RR 0.32 [0.04, 2.64]
Studies not reported
Low

Antibiotics vs placebo or no treatment

Urinary tract infection ‐ not measured · Women undergoing operative vaginal delivery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for operative vaginal delivery 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found