What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 1 · 33.3%Moderate 1 · 33.3%High 0 · 0%

Antibiotics vs antibiotics alone

Neonatal sepsis · women in labor with management of intra‐amniotic infection

Antibiotics showed no clear difference in neonatal sepsis compared with antibiotics (low certainty).

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
RR 1.07 [0.4, 2.86]
2 studies · 163 participants
Low

Antibiotics vs no treatment during postpartum period

Neonatal sepsis · women with management of intra‐amniotic infection

It is very uncertain whether antibiotics changes neonatal sepsis compared with no treatment during postpartum period (very low certainty).

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
RR 1.11 [0.23, 5.27]
1 study · 55 participants
Very low

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Neonatal sepsis · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in neonatal sepsis compared with after neonatal umbilical cord clamping (moderate certainty).

1 finding from 1 review

Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing… 2014 · Cochrane Headline outcomes only
RR 0.76 [0.51, 1.13]
5 studies · 2907 participants
Moderate