Antibiotics vs no treatment or placebo on top of topical antibiotics
Hearing · people (of any age) with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
13 questions · 14 findings · 6 reviews
No studies found 1 · 7.1%GRADE not reported 0 · 0%Very low 10 · 71.4%Low 3 · 21.4%Moderate 0 · 0%High 0 · 0%
Antibiotics vs no treatment
Hearing · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
- no estimate extractedStudies not reportedLow
Antibiotics vs placebo
Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether antibiotics changes hearing ‐ return to normal hearing (as complete improvement in… compared with placebo (very low certainty).
1 finding from 1 review
- Peto OR 9.59 [3.51, 26.18]Studies not reportedVery low
Antibiotics vs no treatment or placebo on top of topical antibiotics
Hearing ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
1 finding from 1 review
- no estimate extracted1 study · 38 participantsVery low
Topical antibiotics with steroids vs topical antibiotics
Hearing · people (of any age) with chronic suppurative otitis media or ear discharge
2 findings from 1 review
- Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 135 participantsVery low
- Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 419 participantsVery low
Topical antibiotics vs placebo/no treatment
Hearing · patients with mucopurulent otorrhoea
1 finding from 1 review
- no estimate extracted1 study · 35 participantsVery low
Topical antibiotics vs acetic acid
Hearing · chronic suppurative otitis media
1 finding from 1 review
- Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 107 participantsVery low
Antibiotics vs no treatment/placebo
Hearing · children with CSOM
1 finding from 1 review
- no estimate extracted1 study · 33 participantsVery low
Topical quinolone vs povidone‐iodine
Hearing · chronic suppurative otitis media
1 finding from 1 review
- Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 40 participantsVery low
Topical antibiotics with steroids vs placebo/no treatment
Hearing · chronic suppurative otitis media
1 finding from 1 review
- Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 123 participantsVery low
Antibiotics vs no treatment or placebo on top of topical antiseptics
Hearing · schoolchildren with CSOM
1 finding from 1 review
- no estimate extracted1 study · 204 participantsVery low
Topical quinolone vs boric acid
Average change in hearing from baseline · chronic suppurative otitis media
1 finding from 1 review
- Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 390 participantsLow
Gastrointestinal adverse events in people taking macrolide antibiotics vs placebo
Hearing loss · any indication
Other adverse events in people taking macrolide antibiotics showed no clear difference in hearing loss compared with placebo (low certainty).
1 finding from 1 review
- Adverse events in people taking macrolide antibiotics versus placebo for any indication 2019 · Cochrane Headline outcomes onlyOR 1.3 [1, 1.7]4 studies · 1369 participantsLow