Antibiotics vs placebo
- Antibiotics for exacerbations of chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes onlyno estimate extracted1 study · 94 participantsModerate
Antibiotics showed no clear difference in all‐cause mortality ‐ inpatients compared with placebo (moderate certainty).
Antibiotics probably leads to lower all‐cause mortality ‐ ICU patients compared with placebo (moderate certainty).
Antibiotics showed no clear difference in adverse events ‐ diarrhoea compared with placebo overall (moderate certainty).
The review found no eligible studies for this question.
Antibiotics showed no clear difference in symptomatic UTI compared with no treatment (low certainty).
Antibiotics showed no clear difference in antimicrobial resistance compared with no treatment (low certainty).
Antibiotics showed no clear difference in all‐cause mortality compared with no treatment (low certainty).
Antibiotics showed no clear difference in graft loss compared with no treatment (low certainty).
Antibiotics showed no clear difference in acute graft rejection compared with no treatment (low certainty).
Antibiotics showed no clear difference in hospitalisation for UTI compared with no treatment (low certainty).
Antibiotics showed no clear difference in number of participants who were not cured at compared with placebo or no treatment (low certainty).
Antibiotics showed no clear difference in number of participants rehospitalised for a respiratory illness compared with placebo or no treatment (low certainty).
Antibiotics showed no clear difference in proportion of participants with recurrent wheeze compared with placebo or no treatment (low certainty).
Antibiotics probably leads to higher complete resolution of OME at 2 to 3 months compared with placebo, no treatment or therapy of unproven effectiveness (moderate certainty).
Antibiotics may leads to higher adverse effects compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
Antibiotics may leads to higher complete resolution of OME at more than 6 months compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
Antibiotics showed no clear difference in insertion of ventilation tubes compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
Antibiotics showed no clear difference in tympanic membrane sequelae compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).