Serious neonatal morbidity
It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes serious neonatal morbidity (Reported in Miller 2014 as 'composite… compared with cervical cerclage alone (very low certainty).
1 finding from 1 review
Perinatal loss: all ‐ including miscarriages and stillbirth (Note: data not available for neonatal death)
It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes perinatal loss: all ‐ including miscarriages and stillbirth (Note:… compared with cervical cerclage alone (very low certainty).
1 finding from 1 review
Baby discharged home healthy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death of the baby before discharge: neonatal death
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Stillbirth (death after 24 weeks inutero)
1 finding from 1 review
Preterm birth less than 34 weeks' gestation
It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes preterm birth < 34 completed weeks of pregnancy compared with cervical cerclage alone (very low certainty).
1 finding from 1 review
Number of participants with symptomatic UTI · primary VUR
Antibiotic prophylaxis showed no clear difference in symptomatic UTI by 1 to 2 years: antibiotics versus no prophylaxis compared with surveillance or no treatment (low certainty).
2 findings from 1 review
Febrile UTI by 1 to 2 years: antibiotics versus no prophylaxis · primary VUR
Antibiotic prophylaxis showed no clear difference in febrile UTI by 1 to 2 years: antibiotics versus no prophylaxis compared with surveillance or no treatment (low certainty).
1 finding from 1 review
Adverse effects of antibiotics · women with episiotomy repair following vaginal birth
1 finding from 1 review
Adverse events due to periodontal therapy · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes adverse events due to periodontal therapy compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
Cardiovascular events · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all cardiovascular events compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
All CVD-related death · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all CVD-related death compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
All‐cause death · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all-cause death compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
CRP (mg/dL) at end of study · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
1 finding from 1 review
Fibrinogen · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
1 finding from 1 review
Adverse effects of antibiotics (skin rash) · Women who had normal vaginal births
It is very uncertain whether routine antibiotic prophylaxis changes adverse effects of antibiotics (skin rash) compared with no treatment or placebo (very low certainty).
1 finding from 1 review
Implant failure · People with at least one dental implant affected by perimplantitis
Implant surface smoothening added to systemic antibiotics +… showed no clear difference in implant failure compared with no implant surface smoothening (same surgical protocol); GRADE not reported.
1 finding from 1 review
Complications and side effects · People with at least one dental implant affected by perimplantitis
1 finding from 1 review
Neonatal mortality ‐ oral + injectable antibiotics · neonates with sepsis
Comparison 1: route of antibiotic showed no clear difference in neonatal mortality ‐ oral + injectable antibiotics compared with standard care (moderate certainty).
1 finding from 1 review
Adverse effects of antibiotics · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure
The review found no eligible studies for this question.
1 finding from 1 review