Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

888 questions · 936 findings · 109 reviews

No studies found 196 · 20.9%GRADE not reported 88 · 9.4%Very low 226 · 24.1%Low 217 · 23.2%Moderate 152 · 16.2%High 57 · 6.1%

Antibiotics vs placebo

Recurrence · sexual partners of women with bacterial vaginosis

It is very uncertain whether any antibiotic treatment changes recurrence compared with placebo (very low certainty).

2 findings from 1 review

Antibiotics vs placebo

Clinical improvement · sexual partners of women with bacterial vaginosis

Any antibiotic treatment showed no clear difference in clinical improvement compared with placebo (high certainty).

2 findings from 1 review

Antibiotics vs placebo

Symptomatic improvement · sexual partners of women with bacterial vaginosis

Any antibiotic treatment showed no clear difference in symptomatic improvement during the first week compared with placebo (high certainty).

3 findings from 1 review

Prophylactic antibiotics vs placebo

Preterm prelabour rupture of membranes · women in the second or third trimester of pregnancy before labour and delivery

Prophylactic antibiotics showed no clear difference in preterm prelabour rupture of membranes compared with placebo (low certainty).

1 finding from 1 review

Prophylactic antibiotics vs placebo

Puerperal sepsis/postpartum endometritis · women in the second or third trimester of pregnancy before labour and delivery

Prophylactic antibiotics probably leads to lower puerperal sepsis/postpartum endometritis compared with placebo (moderate certainty).

1 finding from 1 review

Oral plus nebulised antibiotics vs oral antibiotics plus nebulised placebo

Quality of life: CFQ‐R respiratory domain: absolute change from baseline · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
1 finding from 1 review