Frequency of hospital admissions for pulmonary exacerbations ‐ not measured · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Summary of findings: anti‐pseudomonal antibiotics may leads to lower pulmonary exacerbations: frequency of one or more hospital admissions compared with placebo (low certainty).
1 finding from 1 review
Quality of life: lost school or working days · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
1 finding from 1 review
Survival: number of deaths · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Summary of findings: anti‐pseudomonal antibiotics showed no clear difference in survival: number of deaths compared with placebo (low certainty).
1 finding from 1 review
Antibiotic resistance: frequency of tobramycin‐resistant P aeruginosa · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Summary of findings: anti‐pseudomonal antibiotics showed no clear difference in antibiotic resistance: frequency of tobramycin‐resistant P aeruginosa compared with placebo (moderate certainty).
1 finding from 1 review
Adverse events · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
1 finding from 1 review
Any adverse events · people with cancer who have febrile neutropenia
It is very uncertain whether adverse events with anti‐gram‐positive antibiotics changes any adverse events compared with placebo (very low certainty).
1 finding from 1 review
Surgical site infection · women with urinary stress incontinence undergoing continence surgery
It is very uncertain whether prophylactic antibiotics (single or combined drugs) changes number of surgical site infections (SSIs) before discharge compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Number of major adverse effects defined by the study, before discharge · women with urinary stress incontinence undergoing continence surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of symptomatic UTIs or bacteriuria before discharge · women with urinary stress incontinence undergoing continence surgery
It is very uncertain whether prophylactic antibiotics (single or combined drugs) changes number of symptomatic UTIs or bacteriuria before discharge compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Febrile morbidity · women with urinary stress incontinence undergoing continence surgery
It is very uncertain whether prophylactic antibiotics (single or combined drugs) changes number of women with febrile morbidity at hospital discharge compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Number of women with sepsis or bacteraemia at hospital discharge · women with urinary stress incontinence undergoing continence surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mesh exposure · women with urinary stress incontinence undergoing continence surgery
It is very uncertain whether prophylactic antibiotics (single or combined drugs) changes number of mesh exposures within six weeks after the operation compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Cure: short‐term success · patients on maintenance HD with CRBSI
It is very uncertain whether systemic antibiotics plus antibiotic lock solutions plus tissue… changes cure: short‐term success compared with systemic antibiotics plus antibiotic lock solutions plus heparin (very low certainty).
1 finding from 1 review
RR 0.92 [0.74, 1.15]
18 participants
Very low
Cure: long‐term success · patients on maintenance HD with CRBSI
It is very uncertain whether systemic antibiotics plus antibiotic lock solutions plus tissue… changes cure: long‐term success compared with systemic antibiotics plus antibiotic lock solutions plus heparin (very low certainty).
1 finding from 1 review
RR 64 [0.38, 1.06]
18 participants
Very low
Cure: infection‐free survival · patients on maintenance HD with CRBSI
1 finding from 1 review
no estimate extracted
18 participants
Very low
Stenosis or thrombosis of vascular access site after catheter removal · patients on maintenance HD with CRBSI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death · patients on maintenance HD with CRBSI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Development of antibiotic resistance · patients on maintenance HD with CRBSI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · patients on maintenance HD with CRBSI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall failure (disregarding modifications) · people with cancer who have febrile neutropenia
Treatment failure with anti‐gram‐positive antibiotics showed no clear difference in overall failure (disregarding modifications) compared with placebo (low certainty).
1 finding from 1 review