Number of participants experiencing shunt infection after administration of intravenous antibiotic prophylaxis · CSF‐shunt infections
Antibiotic prophylaxis may leads to lower number of participants experiencing shunt infection after… compared with no antibiotic prophylaxis / standard care (low certainty).
1 finding from 1 review
Number of participants experiencing shunt infection after administration of intrathecal antibiotic prophylaxis · CSF‐shunt infections
Antibiotic prophylaxis showed no clear difference in number of participants experiencing shunt infection after… compared with no antibiotic prophylaxis / standard care (low certainty).
1 finding from 1 review
Number of participants experiencing shunt infection after implantation of antibiotic impregnated catheters · CSF‐shunt infections
It is very uncertain whether antibiotic prophylaxis changes number of participants experiencing shunt infection after… compared with no antibiotic prophylaxis / standard care (very low certainty).
1 finding from 1 review
Surgical site infection · solid organ transplant recipients
It is very uncertain whether antibiotics changes surgical site infections* Time frame: 2 to 6 weeks compared with no antibiotics (very low certainty).
1 finding from 1 review
Death (any case) Time frame: 2 to 4 weeks · solid organ transplant recipients
It is very uncertain whether antibiotics changes death (any case) Time frame: 2 to 4 weeks compared with no antibiotics (very low certainty).
1 finding from 1 review
Graft loss including death · solid organ transplant recipients
It is very uncertain whether antibiotics changes graft loss (including death with functioning graft) Time frame: 2… compared with no antibiotics (very low certainty).
1 finding from 1 review
UTI · solid organ transplant recipients
It is very uncertain whether antibiotics changes other infection: UTI Time frame: 2 to 6 weeks compared with no antibiotics (very low certainty).
1 finding from 1 review
Other infection: septicaemia Time frame: 2 to 6 weeks · solid organ transplant recipients
It is very uncertain whether antibiotics changes other infection: septicaemia Time frame: 2 to 6 weeks compared with no antibiotics (very low certainty).
1 finding from 1 review
Other infection: pneumonia Time frame: 30 days · solid organ transplant recipients
It is very uncertain whether antibiotics changes other infection: pneumonia Time frame: up to 6 weeks compared with no antibiotics (very low certainty).
1 finding from 1 review
Adverse drug reactions · solid organ transplant recipients
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbations · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics probably leads to lower number of people with one or more exacerbations WMD of compared with placebo (moderate certainty).
1 finding from 1 review
Annual Exacerbation Rates · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics probably leads to lower rate of exacerbation per patient/year WMD of compared with placebo (moderate certainty).
1 finding from 1 review
HRQoL: total score · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
1 finding from 1 review
All‐cause mortality WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics showed no clear difference in all‐cause mortality WMD of compared with placebo (moderate certainty).
1 finding from 1 review
Serious adverse events WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics showed no clear difference in serious adverse events WMD of compared with placebo (moderate certainty).
1 finding from 1 review
Any adverse event WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics showed no clear difference in any adverse event WMD of compared with placebo (moderate certainty).
1 finding from 1 review
FEV1 · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
1 finding from 1 review
Incidence of confirmed sepsis in first 28 days · symptomatic neonates born through meconium‐stained amniotic fluid
1 finding from 1 review
Incidence of suspected sepsis · asymptomatic neonates born through meconium‐stained amniotic fluid
1 finding from 1 review
Incidence of mechanical ventilation · asymptomatic neonates born through meconium‐stained amniotic fluid
Antibiotics showed no clear difference in incidence of mechanical ventilation compared with control (no antibiotics) (low certainty).
1 finding from 1 review